Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Terazosin [INN:BAN]
RN: 63590-64-7
UNII: 8L5014XET7
InChIKey: VCKUSRYTPJJLNI-UHFFFAOYSA-N

Note

  • Induces decreased blood pressure; used in the treatment of benign prostatic hyperplasia.

Molecular Formula

  • C19-H25-N5-O4

Molecular Weight

  • 387.4375
 

Classification Codes

  • Adrenergic Agents
  • Adrenergic alpha-1 Receptor Antagonists
  • Adrenergic alpha-Antagonists
  • Adrenergic Antagonists
  • Drug / Therapeutic Agent
  • Neurotransmitter Agents
  • Urological Agents

Names and Synonyms

Name of Substance

  • Terazosin
  • Terazosin [INN:BAN]

Synonyms

  • 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine
  • Blavin
  • Flumarc
  • Fosfomic
  • Terazosin
  • Terazosina
  • Terazosina [INN-Spanish]
  • Terazosine
  • Terazosine [INN-French]
  • Terazosinum
  • Terazosinum [INN-Latin]
  • UNII-8L5014XET7
  • Vasomet

Systematic Name

  • Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-

Registry Numbers

CAS Registry Number

  • 63590-64-7

FDA UNII

  • 8L5014XET7

Related Registry Numbers

  • 63074-08-8 (hydrochloride)
  • 70024-40-7 (mono-hydrochloride, dihydrate)

System Generated Number

  • 0063590647

Structure Descriptors

InChI

1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)

InChIKey

VCKUSRYTPJJLNI-UHFFFAOYSA-N

Smiles

COc1cc2c(cc1OC)nc(nc2N)N3CCN(CC3)C(=O)C4CCCO4

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo oral 3gm/kg (3000mg/kg)   United States Patent Document. Vol. #4734418,

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 273 deg C   EXP
log P (octanol-water) 1.470 (none)   EST
Atmospheric OH Rate Constant 2.64E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.