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Substance Name: Nilutamide [USAN:INN:BAN]
RN: 63612-50-0
UNII: 51G6I8B902
InChIKey: XWXYUMMDTVBTOU-UHFFFAOYSA-N
Classification Codes
- Androgen Antagonists
- Antineoplastic
- Antineoplastic Agents
- Drug / Therapeutic Agent
- Hormone Antagonists
- Hormones, Hormone Substitutes, and Hormone Antagonists
- Reproductive Effect
Molecular Formula
- C12-H10-F3-N3-O4
Molecular Weight
- 317.222
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Names and Synonyms
Name of Substance
- Nilutamide
- Nilutamide [USAN:INN:BAN]
Synonyms
- 1-(3'-Trifluoromethyl-4'-nitrophenyl)-4,4-dimethylimidazolidine-2,5-dione
- 2,4-Imidazolidinedione, 5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-
- 5,5-Dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-2,4-imidazolidinedione
- 5,5-Dimethyl-3-(alpha,alpha,alpha-trifluoro-4-nitro-m-tolyl)hydantoin
- 5-24-05-00358 (Beilstein Handbook Reference)
- Anandron
- BRN 0841906
- Nilandron
- Nilandrone
- Nilutamida
- Nilutamida [Spanish]
- Nilutamide
- Nilutamidum
- Nilutamidum [Latin]
- NSC 758683
- Ru 23908
- RU 23908-10
- RU-23908
- UNII-51G6I8B902
Systematic Names
- 2,4-Imidazolidinedione, 5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-
- 5,5-Dimethyl-3-(alpha,alpha,alpha-trifluoro-4-nitro-m-tolyl)hydantoin
Registry Numbers
CAS Registry Number
- 63612-50-0
FDA UNII
- 51G6I8B902
System Generated Number
- 0063612500
Structure Descriptors
InChI
InChI=1S/C12H10F3N3O4/c1-11(2)9(19)17(10(20)16-11)6-3-4-8(18(21)22)7(5-6)12(13,14)15/h3-5H,1-2H3,(H,16,20)InChIKey
XWXYUMMDTVBTOU-UHFFFAOYSA-NSmiles
CC1(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 150mg/kg (150mg/kg) | Drugs of the Future. Vol. 12, Pg. 763, 1987. | |
mouse | LD50 | oral | 200mg/kg (200mg/kg) | Drugs of the Future. Vol. 12, Pg. 763, 1987. | |
rat | LD50 | intraperitoneal | 125mg/kg (125mg/kg) | Drugs of the Future. Vol. 12, Pg. 763, 1987. | |
rat | LD50 | oral | 195mg/kg (195mg/kg) | Drugs of the Future. Vol. 12, Pg. 763, 1987. |