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Substance Name: Brofaromine [INN]
RN: 63638-91-5
UNII: 6WV4B8Q07H
InChIKey: WZXHSWVDAYOFPE-UHFFFAOYSA-N

Note

  • Short-acting specific type A monoamine oxidase inhibitor.

Molecular Formula

  • C14-H16-Br-N-O2

Molecular Weight

  • 310.189
 

Classification Codes

  • Drug / Therapeutic Agent
  • Enzyme Inhibitors
  • Monoamine Oxidase Inhibitors
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Names and Synonyms

Name of Substance

  • Brofaromine
  • Brofaromine [INN]

Synonyms

  • 4-(7-Bromo-5-methoxy-2-benzofuranyl)piperidine
  • Brofaremine
  • Brofaromina
  • Brofaromina [Spanish]
  • Brofaromine
  • Brofarominum
  • Brofarominum [Latin]
  • CGP 11305
  • UNII-6WV4B8Q07H

Systematic Names

  • 4-(7-Bromo-5-methoxy-2-benzofuranyl)piperidine
  • Piperidine, 4-(7-bromo-5-methoxy-2-benzofuranyl)-
  • Piperidine, 4-(7-bromo-5-methoxy-2-benzofuranyl)-, hydrochloride

Registry Numbers

CAS Registry Number

  • 63638-91-5

FDA UNII

  • 6WV4B8Q07H

Related Registry Number

  • 63638-90-4 (hydrochloride)

System Generated Number

  • 0063638915

Structure Descriptors

InChI

1S/C14H16BrNO2/c1-17-11-6-10-7-13(9-2-4-16-5-3-9)18-14(10)12(15)8-11/h6-9,16H,2-5H2,1H3

InChIKey

WZXHSWVDAYOFPE-UHFFFAOYSA-N

Smiles

O(C)c1cc(c2oc(cc2c1)C1CCNCC1)Br

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo oral 300mg/kg (300mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 284, Pg. 983, 1998.