Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Betaxolol [INN:BAN]
RN: 63659-18-7
UNII: O0ZR1R6RZ2
InChIKey: NWIUTZDMDHAVTP-UHFFFAOYSA-N

Note

  • A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.

Molecular Formula

  • C18-H29-N-O3

Molecular Weight

  • 307.4311
 

Classification Codes

  • Adrenergic Agents
  • Adrenergic Antagonists
  • Adrenergic beta-1 Receptor Antagonists
  • Adrenergic beta-Antagonists
  • Antihypertensive Agents
  • Autonomic Agents
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Neurotransmitter Agents
  • Peripheral Nervous System Agents
  • Sympatholytics

Names and Synonyms

Results Name

  • Betaxolol [INN:BAN]

Name of Substance

  • Betaxolol
  • Betaxolol [INN:BAN]

MeSH Heading

  • Betaxolol

Synonyms

  • 1-(4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol
  • Betaxolol
  • Betaxolol S
  • Betaxololum
  • Betaxololum [INN-Latin]
  • SL 75212
  • UNII-O0ZR1R6RZ2

Systematic Name

  • 2-Propanol, 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-

Registry Numbers

CAS Registry Number

  • 63659-18-7

FDA UNII

  • O0ZR1R6RZ2

Related Registry Number

  • 63659-19-8 (hydrochloride)

System Generated Number

  • 0063659187

Structure Descriptors

InChI

1S/C18H29NO3/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3

InChIKey

NWIUTZDMDHAVTP-UHFFFAOYSA-N

Smiles

c1(ccc(cc1)CCOCC1CC1)OCC(CNC(C)C)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 60mg/kg (60mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 18(Suppl,

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 70-72 deg C   EXP
log P (octanol-water) 2.81 (none)   EXP
Water Solubility 451 mg/L 25 EST
Vapor Pressure 1.33E-08 mm Hg 25 EST
Henry's Law Constant 1.45E-13 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.53E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.