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Substance Name: GTP Pyrophosphokinase
RN: 63690-89-1


  • An enzyme that catalyzes reversibly the transfer of a pyrophosphate group from ATP to the 3'-OH group of GDP or GTP with the formation of guanosine 3'-diphosphate 5'-diphosphate or guanosine 3'-diphosphate 5'-triphosphate and AMP. The enzyme, also called stringent factor, is located in the relA gene in stringent strains of bacteria. The above synthesis is induced by mRNA and uncharged tRNA which is bound to the aminoacyl-t-RNA binding site of the ribosome by a codon-specific association. EC
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Names and Synonyms

Name of Substance

  • GTP Pyrophosphokinase

MeSH Heading

  • GTP Pyrophosphokinase


  • ATP Guanosine Phosphate Pyrophosphotransferase
  • ATP-Guanosine Phosphate Pyrophosphotransferase
  • Factor, Stringent
  • Pyrophosphokinase, GTP
  • Pyrophosphotransferase, ATP-Guanosine Phosphate
  • Stringent Factor

Systematic Name

  • ATP:GTP 3'-pyrophosphotransferase

Registry Numbers

CAS Registry Number

  • 63690-89-1

System Generated Number

  • 0063690891