|
|
Substance Name: Ethanol
RN: 64-17-5
InChIKey: LFQSCWFLJHTTHZ-UHFFFAOYSA-N
Note
- A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.
Molecular Formula
- C2-H6-O
Molecular Weight
- 46.0684
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Anti-Infective Agents
- Anti-Infective Agents, Local
- Anti-Infective, Topical
- Central Nervous System Agents
- Central Nervous System Depressants
- Human Data
- Mutation Data
- Pharmaceutic Aid (Solvent)
- Reproductive Effect
- Skin / Eye Irritant
- Solvents
- Tumor Data
Superlist Classification Codes
- Overall Carcinogenic Evaluation: Group 1
- TWA (1000 ppm); Not classifiable as a human carcinogen
- TWA 1000 ppm (1900 mg/m3)
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Results Name
- Ethanol
Name of Substance
- Alcohol
- Alcohol [USP]
- Distilled spirits
- Ethanol
- Ethanol, undenatured
- Ethyl alcohol, undenatured
MeSH Heading
- Ethanol
Synonyms
- 1-Hydroxyethane
- Absolute ethanol
- Aethanol
- Aethanol [German]
- Aethylalkohol
- Aethylalkohol [German]
- AI3-01706
- Alcohol
- Alcohol (ethyl alcohol)
- Alcohol 5% in dextrose 5%
- Alcohol dehydrated
- Alcohol, anhydrous
- Alcohol, diluted
- Alcohol, ethyl
- Alcool ethylique
- Alcool ethylique [French]
- Alcool etilico
- Alcool etilico [Italian]
- Algrain
- Alkohol
- Alkohol [German]
- Alkoholu etylowego
- Alkoholu etylowego [Polish]
- Anhydrol
- Caswell No. 430
- CCRIS 945
- Cologne Spirit
- Dehydrated alcohol
- Denatured alcohol
- Denatured alcohol CD-10
- Denatured alcohol CD-5
- Denatured alcohol CD-5a
- Denatured alcohol SD-1
- Denatured alcohol SD-13a
- Denatured alcohol SD-17
- Denatured alcohol SD-23a
- Denatured alcohol SD-28
- Denatured alcohol SD-30
- Denatured alcohol SD-39b
- Denatured alcohol SD-39c
- Denatured alcohol SD-3a
- Denatured alcohol SD-40m
- Denatured ethanol
- EC 200-578-6
- EINECS 200-578-6
- EPA Pesticide Chemical Code 001501
- Etanolo
- Etanolo [Italian]
- Ethanol
- Ethanol 200 proof
- Ethanol solution
- Ethanol [JAN]
- Ethyl alcohol
- Ethyl alcohol & water, 10%
- Ethyl alcohol & water, 20%
- Ethyl alcohol & water, 30%
- Ethyl alcohol & water, 40%
- Ethyl alcohol & water, 5%
- Ethyl alcohol & water, 50%
- Ethyl alcohol & water, 60%
- Ethyl alcohol & water, 70%
- Ethyl alcohol & water, 80%
- Ethyl alcohol & water, 95%
- Ethyl alcohol & water, 96%
- Ethyl alcohol anhydrous
- Ethyl alcohol usp
- Ethyl hydrate
- Ethyl hydroxide
- Ethylalcohol
- Ethylalcohol [Dutch]
- EtOH
- Etylowy alkohol
- Etylowy alkohol [Polish]
- FEMA No. 2419
- FEMA Number 2419
- Fermentation alcohol
- Grain alcohol
- HSDB 82
- Hydroxyethane
- Jaysol S
- Methylcarbinol
- Molasses alcohol
- NCI-C03134
- NSC 85228
- Potato alcohol
- SD Alchol 23-hydrogen
- Spirits of wine
- Tecsol
- Tecsol C
- UNII-3K9958V90M
- UNII-7528N5H79B
Systematic Names
- Ethanol
- Ethyl alcohol
Superlist Names
- Ethanol
- Ethyl alcohol
- Ethyl alcohol and water
- Ethyl alcohol in alcoholic beverages
Mixture Names
- Ru-Tuss Expectorant
- Ru-Tuss Hydrocodone Liquid
- Ru-Tuss Liquid
- SDM No. 37
Registry Numbers
CAS Registry Number
- 64-17-5
FDA UNIIs
- 3K9958V90M
- 7528N5H79B
Other Registry Numbers
- 121182-78-3
- 8000-16-6
- 8024-45-1
System Generated Number
- 0000064175
Structure Descriptors
InChI
InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3InChIKey
LFQSCWFLJHTTHZ-UHFFFAOYSA-NSmiles
CCOToxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | intravenous | 3945mg/kg (3945mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955. | |
cat | LDLo | oral | 6gm/kg (6000mg/kg) | GASTROINTESTINAL: GASTRITIS KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" | Journal of Pharmacology and Experimental Therapeutics. Vol. 56, Pg. 117, 1936. |
chicken | LDLo | intravenous | 8216mg/kg (8216mg/kg) | VASCULAR: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 60, Pg. 312, 1937. |
chicken | LDLo | subcutaneous | 5gm/kg (5000mg/kg) | "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931. | |
child | LDLo | oral | 2gm/kg (2000mg/kg) | LIVER: FATTY LIVER DEGERATION BLOOD: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Archiv fuer Toxikologie. Vol. 17, Pg. 183, 1958. |
child | TDLo | oral | 14400mg/kg/30 (14400mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: COMA GASTROINTESTINAL: NAUSEA OR VOMITING | Acta Paediatrica Scandinavica. Vol. 74, Pg. 977, 1985. |
dog | LDLo | intraperitoneal | 3gm/kg (3000mg/kg) | British Journal of Industrial Medicine. Vol. 1, Pg. 207, 1944. | |
dog | LDLo | intravenous | 1600mg/kg (1600mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" | Toxicology and Applied Pharmacology. Vol. 18, Pg. 60, 1971. |
dog | LDLo | oral | 5500mg/kg (5500mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955. | |
dog | LDLo | subcutaneous | 6gm/kg (6000mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955. | |
frog | LDLo | parenteral | 36gm/kg (36000mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 296, 1935. |
frog | LDLo | subcutaneous | 7100mg/kg (7100mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 128, 1955. | |
guinea pig | LCLo | inhalation | 21900ppm (21900ppm) | FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 99, 1970. | |
guinea pig | LD50 | intraperitoneal | 3414mg/kg (3414mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
guinea pig | LD50 | oral | 5560mg/kg (5560mg/kg) | Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941. | |
hamster | LD50 | intraperitoneal | 5068mg/kg (5068mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
human | LDLo | oral | 1400mg/kg (1400mg/kg) | BEHAVIORAL: SLEEP BEHAVIORAL: HEADACHE GASTROINTESTINAL: NAUSEA OR VOMITING | Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 44, 1974. |
infant | LDLo | subcutaneous | 19440mg/kg (19440mg/kg) | BEHAVIORAL: COMA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | American Journal of Clinical Pathology. Vol. 5, Pg. 466, 1935. |
infant | TDLo | oral | 11712uL/kg (11.712mL/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) BEHAVIORAL: GENERAL ANESTHETIC | Journal of UOEH Vol. 9, Pg. 53, 1987. |
mammal (species unspecified) | LD50 | intraperitoneal | 4300mg/kg (4300mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Toxicology and Applied Pharmacology. Vol. 13, Pg. 358, 1968. |
man | TDLo | oral | 1430ug/kg (1.43mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ANTIPSYCHOTIC BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 197, Pg. 488, 1976. |
man | TDLo | oral | 3371uL/kg (3.371mL/kg) | BEHAVIORAL: EXCITEMENT BEHAVIORAL: COMA BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) | Veterinary and Human Toxicology. Vol. 21, Pg. 272, 1979. |
man | TDLo | oral | 50mg/kg (50mg/kg) | GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION GASTROINTESTINAL: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 56, Pg. 117, 1936. |
man | TDLo | oral | 700mg/kg (700mg/kg) | BEHAVIORAL: CHANGES IN PSYCHOPHYSIOLOGICAL TESTS | Neurobehavioral Toxicology and Teratology. Vol. 8, Pg. 77, 1986. |
man | TDLo | oral | 22500mg/kg/4W (22500mg/kg) | ENDOCRINE: OTHER CHANGES BLOOD: OTHER CHANGES | Clinical Endocrinology Vol. 25, Pg. 143, 1986. |
mouse | LC50 | inhalation | 39gm/m3/4H (39000mg/m3) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 26(8), Pg. 53, 1982. | |
mouse | LD50 | intraperitoneal | 528mg/kg (528mg/kg) | Strahlentherapie. Vol. 127, Pg. 245, 1965. | |
mouse | LD50 | intravenous | 1973mg/kg (1973mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 128, 1955. | |
mouse | LD50 | oral | 3450mg/kg (3450mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 32(3), Pg. 31, 1967. | |
mouse | LD50 | subcutaneous | 8285mg/kg (8285mg/kg) | FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 99, 1970. | |
pigeon | LDLo | subcutaneous | 5gm/kg (5000mg/kg) | "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931. | |
rabbit | LD50 | intraperitoneal | 963mg/kg (963mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
rabbit | LD50 | intravenous | 2374mg/kg (2374mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
rabbit | LD50 | oral | 6300mg/kg (6300mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955. | |
rabbit | LDLo | skin | 20gm/kg (20000mg/kg) | "Alcohols: Their Chemistry, Properties and Manufacture," Monick, J.A., New York, Reinhold Book, 1968Vol. -, Pg. 72, 1968. | |
rabbit | LDLo | subcutaneous | 20gm/kg (20000mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 651, 1980. | |
rat | LC50 | inhalation | 20000ppm/10H (20000ppm) | Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 44, 1974. | |
rat | LD50 | intraarterial | 11mg/kg (11mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA | Toxicology and Applied Pharmacology. Vol. 18, Pg. 60, 1971. |
rat | LD50 | intraperitoneal | 3600ug/kg (3.6mg/kg) | Pharmacology: International Journal of Experimental and Clinical Pharmacology. Vol. 2, Pg. 27, 1969. | |
rat | LD50 | intravenous | 1440mg/kg (1440mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Toxicology and Applied Pharmacology. Vol. 18, Pg. 60, 1971. |
rat | LD50 | oral | 7060mg/kg (7060mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Toxicology and Applied Pharmacology. Vol. 16, Pg. 718, 1970. |
women | TDLo | oral | 1200mg/kg/3H (1200mg/kg) | BLOOD: OTHER CHANGES ENDOCRINE: OTHER CHANGES ENDOCRINE: CHANGE IN GONADOTROPINS | Alcoholism: Clinical and Experimental Research. Vol. 7, Pg. 289, 1983. |
women | TDLo | oral | 256gm/kg/12W (256000mg/kg) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" ENDOCRINE: EFFECT ON MENSTRUAL CYSLE | JAMA, Journal of the American Medical Association. Vol. 238, Pg. 2143, 1977. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | -1.14E+02 | deg C | EXP | |
Boiling Point | 78.2 | deg C | EXP | |
pKa Dissociation Constant | 15.9 | (none) | 25 | EXP |
log P (octanol-water) | -0.31 | (none) | EXP | |
Water Solubility | 1.00E+06 | mg/L | 25 | EXP |
Vapor Pressure | 59.3 | mm Hg | 25 | EXP |
Henry's Law Constant | 5.00E-06 | atm-m3/mole | 25 | EXP |
Atmospheric OH Rate Constant | 3.27E-12 | cm3/molecule-sec | 25 | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.