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Substance Name: Ethanol
RN: 64-17-5
InChIKey: LFQSCWFLJHTTHZ-UHFFFAOYSA-N

Note

  • A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.

Molecular Formula

  • C2-H6-O

Molecular Weight

  • 46.0684
 

Classification Codes

Classification Codes

  • Anti-Infective Agents
  • Anti-Infective Agents, Local
  • Anti-Infective, Topical
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Human Data
  • Mutation Data
  • Pharmaceutic Aid (Solvent)
  • Reproductive Effect
  • Skin / Eye Irritant
  • Solvents
  • Tumor Data

Superlist Classification Codes

  • Overall Carcinogenic Evaluation: Group 1
  • TWA (1000 ppm); Not classifiable as a human carcinogen
  • TWA 1000 ppm (1900 mg/m3)

Names and Synonyms

Results Name

  • Ethanol

Name of Substance

  • Alcohol
  • Alcohol [USP]
  • Distilled spirits
  • Ethanol
  • Ethanol, undenatured
  • Ethyl alcohol, undenatured

MeSH Heading

  • Ethanol

Synonyms

  • 1-Hydroxyethane
  • Absolute ethanol
  • Aethanol
  • Aethanol [German]
  • Aethylalkohol
  • Aethylalkohol [German]
  • AI3-01706
  • Alcohol
  • Alcohol (ethyl alcohol)
  • Alcohol 5% in dextrose 5%
  • Alcohol dehydrated
  • Alcohol, anhydrous
  • Alcohol, diluted
  • Alcohol, ethyl
  • Alcool ethylique
  • Alcool ethylique [French]
  • Alcool etilico
  • Alcool etilico [Italian]
  • Algrain
  • Alkohol
  • Alkohol [German]
  • Alkoholu etylowego
  • Alkoholu etylowego [Polish]
  • Anhydrol
  • Caswell No. 430
  • CCRIS 945
  • Cologne Spirit
  • Dehydrated alcohol
  • Denatured alcohol
  • Denatured alcohol CD-10
  • Denatured alcohol CD-5
  • Denatured alcohol CD-5a
  • Denatured alcohol SD-1
  • Denatured alcohol SD-13a
  • Denatured alcohol SD-17
  • Denatured alcohol SD-23a
  • Denatured alcohol SD-28
  • Denatured alcohol SD-30
  • Denatured alcohol SD-39b
  • Denatured alcohol SD-39c
  • Denatured alcohol SD-3a
  • Denatured alcohol SD-40m
  • Denatured ethanol
  • EC 200-578-6
  • EINECS 200-578-6
  • EPA Pesticide Chemical Code 001501
  • Etanolo
  • Etanolo [Italian]
  • Ethanol
  • Ethanol 200 proof
  • Ethanol solution
  • Ethanol [JAN]
  • Ethyl alcohol
  • Ethyl alcohol & water, 10%
  • Ethyl alcohol & water, 20%
  • Ethyl alcohol & water, 30%
  • Ethyl alcohol & water, 40%
  • Ethyl alcohol & water, 5%
  • Ethyl alcohol & water, 50%
  • Ethyl alcohol & water, 60%
  • Ethyl alcohol & water, 70%
  • Ethyl alcohol & water, 80%
  • Ethyl alcohol & water, 95%
  • Ethyl alcohol & water, 96%
  • Ethyl alcohol anhydrous
  • Ethyl alcohol usp
  • Ethyl hydrate
  • Ethyl hydroxide
  • Ethylalcohol
  • Ethylalcohol [Dutch]
  • EtOH
  • Etylowy alkohol
  • Etylowy alkohol [Polish]
  • FEMA No. 2419
  • FEMA Number 2419
  • Fermentation alcohol
  • Grain alcohol
  • HSDB 82
  • Hydroxyethane
  • Jaysol S
  • Methylcarbinol
  • Molasses alcohol
  • NCI-C03134
  • NSC 85228
  • Potato alcohol
  • SD Alchol 23-hydrogen
  • Spirits of wine
  • Tecsol
  • Tecsol C
  • UNII-3K9958V90M
  • UNII-7528N5H79B

Systematic Names

  • Ethanol
  • Ethyl alcohol

Superlist Names

  • Ethanol
  • Ethyl alcohol
  • Ethyl alcohol and water
  • Ethyl alcohol in alcoholic beverages

Mixture Names

  • Ru-Tuss Expectorant
  • Ru-Tuss Hydrocodone Liquid
  • Ru-Tuss Liquid
  • SDM No. 37

Registry Numbers

CAS Registry Number

  • 64-17-5

FDA UNIIs

  • 3K9958V90M
  • 7528N5H79B

Other Registry Numbers

  • 121182-78-3
  • 8000-16-6
  • 8024-45-1

System Generated Number

  • 0000064175

Structure Descriptors

InChI

InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3

InChIKey

LFQSCWFLJHTTHZ-UHFFFAOYSA-N

Smiles

CCO

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 3945mg/kg (3945mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955.
cat LDLo oral 6gm/kg (6000mg/kg) GASTROINTESTINAL: GASTRITIS

KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS

LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"		 Journal of Pharmacology and Experimental Therapeutics. Vol. 56, Pg. 117, 1936.
chicken LDLo intravenous 8216mg/kg (8216mg/kg) VASCULAR: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 60, Pg. 312, 1937.
chicken LDLo subcutaneous 5gm/kg (5000mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
child LDLo oral 2gm/kg (2000mg/kg) LIVER: FATTY LIVER DEGERATION

BLOOD: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Archiv fuer Toxikologie. Vol. 17, Pg. 183, 1958.
child TDLo oral 14400mg/kg/30 (14400mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: COMA

GASTROINTESTINAL: NAUSEA OR VOMITING		 Acta Paediatrica Scandinavica. Vol. 74, Pg. 977, 1985.
dog LDLo intraperitoneal 3gm/kg (3000mg/kg)   British Journal of Industrial Medicine. Vol. 1, Pg. 207, 1944.
dog LDLo intravenous 1600mg/kg (1600mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: ATAXIA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 Toxicology and Applied Pharmacology. Vol. 18, Pg. 60, 1971.
dog LDLo oral 5500mg/kg (5500mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955.
dog LDLo subcutaneous 6gm/kg (6000mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955.
frog LDLo parenteral 36gm/kg (36000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE		 Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 296, 1935.
frog LDLo subcutaneous 7100mg/kg (7100mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 128, 1955.
guinea pig LCLo inhalation 21900ppm (21900ppm)   FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 99, 1970.
guinea pig LD50 intraperitoneal 3414mg/kg (3414mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
guinea pig LD50 oral 5560mg/kg (5560mg/kg)   Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
hamster LD50 intraperitoneal 5068mg/kg (5068mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
human LDLo oral 1400mg/kg (1400mg/kg) BEHAVIORAL: SLEEP

BEHAVIORAL: HEADACHE

GASTROINTESTINAL: NAUSEA OR VOMITING		 Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 44, 1974.
infant LDLo subcutaneous 19440mg/kg (19440mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 American Journal of Clinical Pathology. Vol. 5, Pg. 466, 1935.
infant TDLo oral 11712uL/kg (11.712mL/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

BEHAVIORAL: GENERAL ANESTHETIC		 Journal of UOEH Vol. 9, Pg. 53, 1987.
mammal (species unspecified) LD50 intraperitoneal 4300mg/kg (4300mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)		 Toxicology and Applied Pharmacology. Vol. 13, Pg. 358, 1968.
man TDLo oral 1430ug/kg (1.43mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: ANTIPSYCHOTIC

BEHAVIORAL: ATAXIA		 Journal of Pharmacology and Experimental Therapeutics. Vol. 197, Pg. 488, 1976.
man TDLo oral 3371uL/kg (3.371mL/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: COMA

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)		 Veterinary and Human Toxicology. Vol. 21, Pg. 272, 1979.
man TDLo oral 50mg/kg (50mg/kg) GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION

GASTROINTESTINAL: OTHER CHANGES		 Journal of Pharmacology and Experimental Therapeutics. Vol. 56, Pg. 117, 1936.
man TDLo oral 700mg/kg (700mg/kg) BEHAVIORAL: CHANGES IN PSYCHOPHYSIOLOGICAL TESTS Neurobehavioral Toxicology and Teratology. Vol. 8, Pg. 77, 1986.
man TDLo oral 22500mg/kg/4W (22500mg/kg) ENDOCRINE: OTHER CHANGES

BLOOD: OTHER CHANGES		 Clinical Endocrinology Vol. 25, Pg. 143, 1986.
mouse LC50 inhalation 39gm/m3/4H (39000mg/m3)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 26(8), Pg. 53, 1982.
mouse LD50 intraperitoneal 528mg/kg (528mg/kg)   Strahlentherapie. Vol. 127, Pg. 245, 1965.
mouse LD50 intravenous 1973mg/kg (1973mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 128, 1955.
mouse LD50 oral 3450mg/kg (3450mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 32(3), Pg. 31, 1967.
mouse LD50 subcutaneous 8285mg/kg (8285mg/kg)   FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 99, 1970.
pigeon LDLo subcutaneous 5gm/kg (5000mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
rabbit LD50 intraperitoneal 963mg/kg (963mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rabbit LD50 intravenous 2374mg/kg (2374mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rabbit LD50 oral 6300mg/kg (6300mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 130, 1955.
rabbit LDLo skin 20gm/kg (20000mg/kg)   "Alcohols: Their Chemistry, Properties and Manufacture," Monick, J.A., New York, Reinhold Book, 1968Vol. -, Pg. 72, 1968.
rabbit LDLo subcutaneous 20gm/kg (20000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 651, 1980.
rat LC50 inhalation 20000ppm/10H (20000ppm)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 44, 1974.
rat LD50 intraarterial 11mg/kg (11mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA		 Toxicology and Applied Pharmacology. Vol. 18, Pg. 60, 1971.
rat LD50 intraperitoneal 3600ug/kg (3.6mg/kg)   Pharmacology: International Journal of Experimental and Clinical Pharmacology. Vol. 2, Pg. 27, 1969.
rat LD50 intravenous 1440mg/kg (1440mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA Toxicology and Applied Pharmacology. Vol. 18, Pg. 60, 1971.
rat LD50 oral 7060mg/kg (7060mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Toxicology and Applied Pharmacology. Vol. 16, Pg. 718, 1970.
women TDLo oral 1200mg/kg/3H (1200mg/kg) BLOOD: OTHER CHANGES

ENDOCRINE: OTHER CHANGES

ENDOCRINE: CHANGE IN GONADOTROPINS		 Alcoholism: Clinical and Experimental Research. Vol. 7, Pg. 289, 1983.
women TDLo oral 256gm/kg/12W (256000mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

ENDOCRINE: EFFECT ON MENSTRUAL CYSLE		 JAMA, Journal of the American Medical Association. Vol. 238, Pg. 2143, 1977.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -1.14E+02 deg C   EXP
Boiling Point 78.2 deg C   EXP
pKa Dissociation Constant 15.9 (none) 25 EXP
log P (octanol-water) -0.31 (none)   EXP
Water Solubility 1.00E+06 mg/L 25 EXP
Vapor Pressure 59.3 mm Hg 25 EXP
Henry's Law Constant 5.00E-06 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 3.27E-12 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.