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Substance Name: Mebutamate [USAN:INN:BAN:JAN]
RN: 64-55-1
UNII: 5H8F175RER
InChIKey: LEROTMJVBFSIMP-UHFFFAOYSA-N

Molecular Formula

  • C10-H20-N2-O4

Molecular Weight

  • 232.278
 

Classification Codes

Classification Codes

  • Antihypertensive
  • Drug / Therapeutic Agent

Superlist Classification Code

  • DEA Schedule IV
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Names and Synonyms

Name of Substance

  • Mebutamate [USAN:INN:BAN:JAN]

Synonyms

  • 2,2-Dicarbamyloxymethyl-3-methylpentane
  • 2-Methyl-2-(1-methylpropyl)-1,3-propanediol dicarbamate
  • 2-Methyl-2-sec-butyl-1,3-propanediol dicarbamate
  • 2-sec-Butyl-2-methyl-1,3-propanediol dicarbamate
  • 2-sec-Butyl-2-methyltrimethylene dicarbamate
  • 4-03-00-00074 (Beilstein Handbook Reference)
  • Axiten
  • BRN 1788226
  • Butatensin
  • Capla
  • Carbamic acid, 2-sec-butyl-2-methyltrimethylene ester
  • Carbuten
  • Dicamoylmethtane
  • Dormate
  • EINECS 200-587-5
  • Encapla
  • Ipotensivo
  • Mebutamat
  • Mebutamate
  • Mebutamato
  • Mebutamato [INN-Spanish]
  • Mebutamatum
  • Mebutamatum [INN-Latin]
  • Mebutina
  • MEGA
  • Mioartrina
  • NO-Press
  • NSC 163921
  • Prean
  • Preminex
  • Sigmafon
  • UNII-5H8F175RER
  • Vallene
  • W 583
  • W-583

Systematic Names

  • 1,3-Propanediol, 2-methyl-2-(1-methylpropyl)-, dicarbamate
  • 1,3-Propanediol, 2-sec-butyl-2-methyl-, dicarbamate
  • Mebutamate

Superlist Names

  • DEA No. 2800
  • Mebutamate

Mixture Name

  • Caplaril

Registry Numbers

CAS Registry Number

  • 64-55-1

FDA UNII

  • 5H8F175RER

System Generated Number

  • 0000064551

Structure Descriptors

InChI

1S/C10H20N2O4/c1-4-7(2)10(3,5-15-8(11)13)6-16-9(12)14/h7H,4-6H2,1-3H3,(H2,11,13)(H2,12,14)

InChIKey

LEROTMJVBFSIMP-UHFFFAOYSA-N

Smiles

NC(OCC(C)(COC(N)=O)[C@@H](C)CC)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 100mg/kg (100mg/kg)   Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
mouse LD50 intraperitoneal 460mg/kg (460mg/kg)   Journal of Medicinal Chemistry. Vol. 12, Pg. 462, 1969.
mouse LD50 oral 550mg/kg (550mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 356, 1961.
rat LD50 intraperitoneal 410mg/kg (410mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 356, 1961.
rat LD50 oral 1160mg/kg (1160mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 356, 1961.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 77 deg C   EXP
log P (octanol-water) 1.400 (none)   EST
Water Solubility 1000 mg/L   EXP
Atmospheric OH Rate Constant 2.10E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.