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Substance Name: Butyrophenone, 4-(3-azaspiro(5.5)undec-3-yl)-4'-fluoro-, hydrochloride
RN: 64-60-8
InChIKey: OOSPTPAVGQFOIZ-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C20-H28-F-N-O.Cl-H

Molecular Weight

  • 353.906
 
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Names and Synonyms

Synonyms

  • 3-((4-p-Fluorophenyl-4-hydroxy)butyl)-3-azaspiro(5.5)undecane hydrochloride
  • 4-(3-Azaspiro(5.5)undec-3-yl)-4'-fluoro-butyrophenone hydrochloride
  • NSC 90825

Systematic Name

  • Butyrophenone, 4-(3-azaspiro(5.5)undec-3-yl)-4'-fluoro-, hydrochloride

Registry Numbers

CAS Registry Number

  • 64-60-8

System Generated Number

  • 0000064608

Molecular Formulas

Molecular Formula

  • C20-H28-F-N-O.Cl-H

Molecular Formula Fragments

  • C20-H28-F-N-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C20H28FNO.ClH/c21-18-8-6-17(7-9-18)19(23)5-4-14-22-15-12-20(13-16-22)10-2-1-3-11-20;/h6-9H,1-5,10-16H2;1H

InChIKey

OOSPTPAVGQFOIZ-UHFFFAOYSA-N

Smiles

C12(CCN(CCCC(c3ccc(F)cc3)=O)CC1)CCCCC2.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 45mg/kg (45mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANALGESIA
Journal of Medicinal Chemistry. Vol. 8, Pg. 62, 1965.
mouse LD50 oral 120mg/kg (120mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Medicinal Chemistry. Vol. 8, Pg. 62, 1965.
rat LD50 intraperitoneal 60mg/kg (60mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANALGESIA
Journal of Medicinal Chemistry. Vol. 8, Pg. 62, 1965.
rat LD50 oral 200mg/kg (200mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Medicinal Chemistry. Vol. 8, Pg. 62, 1965.