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Substance Name: Zapizolam [INN]
RN: 64098-32-4
UNII: MFF90009B9
InChIKey: FOWABKOXWTZAKY-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C15-H9-Cl2-N5

Molecular Weight

  • 330.1771
 
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Names and Synonyms

Name of Substance

  • Zapizolam [INN]

Synonyms

  • 8-Chloro-6-(2-chlorophenyl)-4H-pyrido(2,3-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine
  • 8-Chloro-6-(o-chlorophenyl)-4H-pyrido(2,3-f)-s-triazolo(4,3-a)(1,4)diazepine
  • BRN 1154881
  • D 13129
  • D-13,129
  • EINECS 264-670-8
  • UNII-MFF90009B9
  • Zapizolam
  • Zapizolamum
  • Zapizolamum [INN-Latin]

Systematic Names

  • 4H-Pyrido(2,3-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine, 8-chloro-6-(2-chlorophenyl)-
  • 8-Chloro-6-(o-chlorophenyl)-4H-pyrido(2,3-f)-s-triazolo(4,3-a)(1,4)diazepine
  • Zapizolam

Registry Numbers

CAS Registry Number

  • 64098-32-4

FDA UNII

  • MFF90009B9

System Generated Number

  • 0064098324

Structure Descriptors

InChI

1S/C15H9Cl2N5/c16-10-4-2-1-3-9(10)14-15-11(5-6-12(17)20-15)22-8-19-21-13(22)7-18-14/h1-6,8H,7H2

InChIKey

FOWABKOXWTZAKY-UHFFFAOYSA-N

Smiles

n1ncn2c1CN=C(c1nc(ccc21)Cl)c1c(cccc1)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 79mg/kg (79mg/kg)   Drugs of the Future. Vol. 7, Pg. 831, 1982.
dog LD50 oral > 10gm/kg (10000mg/kg)   Drugs of the Future. Vol. 7, Pg. 831, 1982.
mouse LD50 oral > 10gm/kg (10000mg/kg)   Drugs of the Future. Vol. 7, Pg. 831, 1982.
rat LD50 intravenous 48500ug/kg (48.5mg/kg)   Drugs of the Future. Vol. 7, Pg. 831, 1982.
rat LD50 oral > 10gm/kg (10000mg/kg)   Drugs of the Future. Vol. 7, Pg. 831, 1982.