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Substance Name: Nilotinib [USAN:INN:BAN]
RN: 641571-10-0
UNII: F41401512X
InChIKey: HHZIURLSWUIHRB-UHFFFAOYSA-N

Note

  • Antineoplastic agent

Classification Code

  • Antineoplastic

Molecular Formula

  • C28-H22-F3-N7-O

Molecular Weight

  • 529.5238
 

Names and Synonyms

Name of Substance

  • 4-Methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide
  • Nilotinib [USAN:INN:BAN]

Synonyms

  • AMN 107
  • AMN107
  • EC 700-544-5
  • HSDB 7842
  • Nilotinib
  • Tasigna
  • UNII-F41401512X

Systematic Names

  • 4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-{(4-(pyridin-3-yl)pyrimidin-2-yl)amino}benzamide
  • Benzamide, 4-methyl-N-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(3-pyridinyl)-2-pyrimidinyl)amino)-
  • N-(3-(3-(1H-Imidazolyl)propoxy)phenyl)-4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzamide

Registry Numbers

CAS Registry Number

  • 641571-10-0

FDA UNII

  • F41401512X

System Generated Number

  • 0641571100

Structure Descriptors

InChI

1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)

InChIKey

HHZIURLSWUIHRB-UHFFFAOYSA-N

Smiles

Cc1ccc(cc1Nc2nccc(n2)c3cccnc3)C(=O)Nc4cc(cc(c4)n5cc(nc5)C)C(F)(F)F