Skip Navigation
ChemIDplus A TOXNET DATABASE Lite•Browse•Advanced

Substance Name: Atracurium
RN: 64228-79-1
UNII: 2GQ1IRY63P
InChIKey: YXSLJKQTIDHPOT-UHFFFAOYSA-N

Note

  • A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.

Molecular Formula

  • C53-H72-N2-O12

Molecular Weight

  • 929.154
 

Classification Codes

  • Cholinergic Agents
  • Cholinergic Antagonists
  • Drug / Therapeutic Agent
  • Human Data
  • Neuromuscular Agents
  • Neuromuscular Blocking Agents
  • Neuromuscular Nondepolarizing Agents
  • Neurotransmitter Agents
  • Nicotinic Antagonists
  • Peripheral Nervous System Agents
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Atracurium

MeSH Heading

  • Atracurium

Synonyms

  • Atracurium
  • BRN 1523633
  • UNII-2GQ1IRY63P

Systematic Names

  • Isoquinolinium, 1,2,3,4-tetrahydro-2,2'-(1,5-pentanediylbis(oxy(3-oxo-3,1-propanediyl)))bis(1-((3,4-dimethoxyphenyl)methyl)-6,7-dimethoxy-2-methyl-
  • Isoquinolinium, 2,2'-(1,5-pentanediylbis(oxy(3-oxo-3,1-propanediyl)))bis(1-((3,4-dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-

Registry Numbers

CAS Registry Number

  • 64228-79-1

FDA UNII

  • 2GQ1IRY63P

Related Registry Number

  • 64228-81-5 (besylate)

System Generated Number

  • 0064228791

Structure Descriptors

InChI

1S/C53H72N2O12/c1-54(22-18-38-32-48(62-7)50(64-9)34-40(38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-37-15-17-45(59-4)47(31-37)61-6/h14-17,30-35,42-43H,11-13,18-29H2,1-10H3/q+2

InChIKey

YXSLJKQTIDHPOT-UHFFFAOYSA-N

Smiles

c12c(cc(OC)c(c1)OC)CC[N@@+]([C@@H]2Cc1cc(c(OC)cc1)OC)(CCC(OCCCCCOC(CC[N@@+]1([C@@H](c2c(cc(OC)c(c2)OC)CC1)Cc1cc(c(OC)cc1)OC)C)=O)=O)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo parenteral 520ug/kg (0.52mg/kg) CARDIAC: PULSE RATE British Medical Journal. Vol. 287, Pg. 247, 1983.