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Substance Name: 1,2-Propanediol dinitrate
RN: 6423-43-4
UNII: 4BY6T6Y8D1
InChIKey: PSXCGTLGGVDWFU-UHFFFAOYSA-N
Note
- Major volatile constituent of Otto Fuel II liquid propellant that causes vasodilation, lowered blood pressure, methemoglobin formation; monoamine oxidase inhibitor.
Molecular Formula
- C3-H6-N2-O6
Molecular Weight
- 166.088
- All
- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Human Data
- Skin / Eye Irritant
Superlist Classification Code
- TWA (0.05 ppm); skin; BEI
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Names and Synonyms
Name of Substance
- 1,2-Propanediol dinitrate
Synonyms
- 1,2-Propanediol dinitrate
- 4-01-00-02497 (Beilstein Handbook Reference)
- BRN 1709968
- EINECS 229-180-0
- HSDB 6823
- Isopropylene nitrate
- NSC 62614
- PGDN
- Propylene dinitrate
- Propylene glycol 1,2-dinitrate
- Propylene glycol dinitrate
- Propylene nitrate
- UNII-4BY6T6Y8D1
Systematic Names
- 1,2-Propanediol, 1,2-dinitrate
- 1,2-Propanediol, dinitrate
- Propane-1,2-diyl dinitrate
Superlist Names
- 1,2-Propanediol, dinitrate
- 1,2-Propylene glycol dinitrate
- Propylene glycol dinitrate
Registry Numbers
CAS Registry Number
- 6423-43-4
FDA UNII
- 4BY6T6Y8D1
System Generated Number
- 0006423434
Structure Descriptors
InChI
1S/C3H6N2O6/c1-3(11-5(8)9)2-10-4(6)7/h3H,2H2,1H3InChIKey
PSXCGTLGGVDWFU-UHFFFAOYSA-NSmiles
C([C@@H](O[N+](=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | subcutaneous | 200mg/kg (200mg/kg) | BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Toxicology and Applied Pharmacology. Vol. 15, Pg. 175, 1969. |
guinea pig | LD50 | intraperitoneal | 402mg/kg (402mg/kg) | American Industrial Hygiene Association Journal. Vol. 34, Pg. 526, 1973. | |
human | TCLo | inhalation | 200ppb/6H (0.2ppm) | BEHAVIORAL: HEADACHE | Toxicology and Applied Pharmacology. Vol. 30, Pg. 377, 1974. |
human | TCLo | inhalation | 1500ppb/5M (1.5ppm) | SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE | Toxicology and Applied Pharmacology. Vol. 30, Pg. 377, 1974. |
monkey | LDLo | intravenous | 410mg/kg (410mg/kg) | BEHAVIORAL: ATAXIA GASTROINTESTINAL: NAUSEA OR VOMITING SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE | Toxicology and Applied Pharmacology. Vol. 22, Pg. 128, 1972. |
mouse | LD50 | intraperitoneal | 1047mg/kg (1047mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | American Industrial Hygiene Association Journal. Vol. 34, Pg. 526, 1973. |
mouse | LD50 | oral | 1525mg/kg (1525mg/kg) | BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 94, 1999. |
mouse | LD50 | subcutaneous | 1208mg/kg (1208mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Toxicology and Applied Pharmacology. Vol. 15, Pg. 175, 1969. |
rat | LD50 | intraperitoneal | 479mg/kg (479mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION | American Industrial Hygiene Association Journal. Vol. 34, Pg. 526, 1973. |
rat | LD50 | oral | 250mg/kg (250mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | American Industrial Hygiene Association Journal. Vol. 34, Pg. 526, 1973. |
rat | LD50 | subcutaneous | 463mg/kg (463mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN | Toxicology and Applied Pharmacology. Vol. 15, Pg. 175, 1969. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Atmospheric OH Rate Constant | 3.20E-13 | cm3/molecule-sec | 25 | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.