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Substance Name: Polypyrimidine tract-binding protein
RN: 139076-35-0


  • A RNA-binding protein that binds to polypyriminidine rich regions in the INTRONS of messenger RNAs. Polypyrimidine tract-binding protein may be involved in regulating the ALTERNATIVE SPLICING of mRNAs since its presence on an intronic RNA region that is upstream of an EXON inhibits the splicing of the exon into the final mRNA product.
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Names and Synonyms

Name of Substance

  • Polypyrimidine tract-binding protein

MeSH Heading

  • Polypyrimidine tract-binding protein


  • Hnrnp-I
  • Hnrnpi
  • p57 Protein
  • pPTB

Systematic Name

  • Protein pPTB (human clone pC15 polypyrimidine tract-binding reduced)

Registry Numbers

CAS Registry Number

  • 139076-35-0

System Generated Number

  • 0139076350