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Substance Name: Gaboxadol [USAN:INN]
RN: 64603-91-4
UNII: K1M5RVL18S
InChIKey: ZXRVKCBLGJOCEE-UHFFFAOYSA-N
Note
- GABA agonist; inhibitor of GABA uptake systems.
Molecular Formula
- C6-H8-N2-O2
Molecular Weight
- 140.1412
Classification Codes
- Analgesics
- Anticonvulsants
- Central Nervous System Agents
- Drug / Therapeutic Agent
- GABA Agents
- GABA Agonists
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Sensory System Agents
- Treatment of Insomnia
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Names and Synonyms
Name of Substance
- Gaboxadol
- Gaboxadol [USAN:INN]
Synonyms
- 4,5,6,7-Tetrahydroisoxazole(5,4-c)pyridin-3-ol
- 4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3-ol
- EINECS 264-963-0
- Gaboxadol
- Gaboxadolum
- Gaboxadolum [Latin]
- Lu 02-030
- MK-0928
- THIP
- UNII-K1M5RVL18S
Systematic Names
- 4,5,6,7-Tetrahydroisoxazole(5,4-c)pyridin-3-ol
- Gaboxadol
- Isoxazolo(5,4-c)pyridin-3(2H)-one, 4,5,6,7-tetrahydro-
Registry Numbers
CAS Registry Number
- 64603-91-4
FDA UNII
- K1M5RVL18S
System Generated Number
- 0064603914
Structure Descriptors
InChI
1S/C6H8N2O2/c9-6-4-1-2-7-3-5(4)10-8-6/h7H,1-3H2,(H,8,9)InChIKey
ZXRVKCBLGJOCEE-UHFFFAOYSA-NSmiles
C1CNCc2c1c(=O)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 98mg/kg (98mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Neuropharmacology. Vol. 21, Pg. 803, 1982. |