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Substance Name: RAM 376
RN: 6474-96-0
InChIKey: MSSJSKXBOBHMMV-AKAGGGOCSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C25-H27-N-O4

Molecular Weight

  • 405.4913
 
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Names and Synonyms

Results Name

  • RAM 376

Synonyms

  • 4,5-alpha-Epoxy-14-hydroxy-3-methoxy-17-phenethylmorphinan-6-one
  • 7,8-Dihydro-14-hydroxy-N-phenethylnorcodeinone
  • BRN 1180216
  • Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-(2-phenylethyl)-, (5-alpha)-
  • Norcodeinone, 7,8-dihydro-14-hydroxy-N-phenethyl-
  • RAM-376

Systematic Name

  • Morphinan-6-one, 4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-phenethyl-

Registry Numbers

CAS Registry Number

  • 6474-96-0

System Generated Number

  • 0006474960

Structure Descriptors

InChI

1S/C25H27NO4/c1-29-19-8-7-17-15-20-25(28)11-9-18(27)23-24(25,21(17)22(19)30-23)12-14-26(20)13-10-16-5-3-2-4-6-16/h2-8,20,23,28H,9-15H2,1H3/t20-,23+,24+,25-/m1/s1

InChIKey

MSSJSKXBOBHMMV-AKAGGGOCSA-N

Smiles

COc1ccc2C[C@H]3N(CCc4ccccc4)CC[C@@]56[C@@H](Oc1c25)C(=O)CC[C@@]36O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 39mg/kg (39mg/kg)   Yakugaku Zasshi. Journal of Pharmacy. Vol. 84, Pg. 280, 1964.