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Substance Name: Lidamidine hydrochloride [USAN]
RN: 65009-35-0
UNII: 3Q1Q4QJV3V
InChIKey: INMBONSHXVMDSX-UHFFFAOYSA-N

Classification Codes

  • Antiperistaltic
  • Drug / Therapeutic Agent

Molecular Formula

  • C11-H16-N4-O.Cl-H

Molecular Weight

  • 256.735
 
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Names and Synonyms

Name of Substance

  • Lidamidine hydrochloride
  • Lidamidine hydrochloride [USAN]

Synonyms

  • 1-(2,6-Dimethylphenyl)-3-methylamidinourea hydrochloride
  • 1-(Methylamidino)-3-(2,6-xylyl)urea monohydrochloride
  • EINECS 265-307-6
  • Lidamidine HCl
  • Lidamidine hydrochloride
  • Lidarral
  • Smodin
  • UNII-3Q1Q4QJV3V
  • Urea, N-(2,6-dimethylphenyl)-N'-(imino(methylamino)methyl)-, monohydrochloride
  • WHR-1142A

Systematic Names

  • 1-(2,6-Dimethylphenyl)-3-(imino(methylamino)methyl)uronium chloride
  • Urea, 1-(2,6-xylyl)-3-methylamidino-, hydrochloride
  • Urea, N-(2,6-dimethylphenyl)-N'-(imino(methylamino)methyl)-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 65009-35-0

FDA UNII

  • 3Q1Q4QJV3V

Related Registry Number

  • 66871-56-5 (Parent)

System Generated Number

  • 0065009350

Molecular Formulas

Molecular Formula

  • C11-H16-N4-O.Cl-H

Molecular Formula Fragments

  • C11-H16-N4-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C11H16N4O.ClH/c1-7-5-4-6-8(2)9(7)14-11(16)15-10(12)13-3;/h4-6H,1-3H3,(H4,12,13,14,15,16);1H

InChIKey

INMBONSHXVMDSX-UHFFFAOYSA-N

Smiles

c1(c(cccc1C)C)NC(NC(NC)=N)=O.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 65mg/kg (65mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 1471, 1978.
mouse LD50 oral 303mg/kg (303mg/kg) SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 1471, 1978.
rat LD50 oral 187mg/kg (187mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 1471, 1978.