|
|
Substance Name: Sulfameter [USAN]
RN: 651-06-9
UNII: 3L179F09D6
InChIKey: GPTONYMQFTZPKC-UHFFFAOYSA-N
Note
- Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Molecular Formula
- C11-H12-N4-O3-S
Molecular Weight
- 280.3068
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Anti-Infective Agents, Urinary
- Antibacterial
- Drug / Therapeutic Agent
- Leprostatic Agents
- Renal Agents
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Name of Substance
- Sulfameter
- Sulfameter [USAN]
- Sulfametoxydiazine [INN]
MeSH Heading
- Sulfameter
Synonyms
- 2-(4-Aminobenzenesulfonamido)-5-methoxypyrimidine
- 2-Sulfanilamido-5-methoxypyrimidin
- 2-Sulfanilamido-5-methoxypyrimidin [German]
- 2-Sulfanilamido-5-methoxypyrimidine
- 4-Amino-N-(5-methoxy-2-pyrimidinyl)benzenesulfonamide
- 5-25-12-00525 (Beilstein Handbook Reference)
- 5-Methoxy-2-sulfanilamidopyrimidine
- AHR-857
- Bayer 5400
- Bayrena
- Berlicid
- BRN 0621130
- Dairena
- Durenat
- Durisan
- EINECS 211-480-8
- I-2586
- Juvoxin
- Kinecid
- Kirocid
- Kiron
- Longasulf
- Methoxypyrimal
- N(sup 1)-(5-Methoxy-2-pyrimidinyl)sulfanilamide
- N1-(5-Methoxy-2-pyrimidinyl)sulfanilamide
- NSC 683528
- SH 613
- Solfametossidiazina
- Solfametossidiazina [DCIT]
- Sulfa-5-methoxypyrimidine
- Sulfameter
- Sulfamethorine
- Sulfamethoxine
- Sulfamethoxydiazine
- Sulfamethoxydin
- Sulfamethoxypyrimidine
- Sulfametin
- Sulfametinum
- Sulfametorine
- Sulfametoxidiazina
- Sulfametoxidiazina [INN-Spanish]
- Sulfametoxipirimidine
- Sulfametoxydiazine
- Sulfametoxydiazinum
- Sulfametoxydiazinum [INN-Latin]
- Sulla
- Sulphameter
- Sulphamethoxydiazine
- Supramid
- Ultrax
- UNII-3L179F09D6
Systematic Names
- Benzenesulfonamide, 4-amino-N-(5-methoxy-2-pyridimidinyl)-
- Benzenesulfonamide, 4-amino-N-(5-methoxy-2-pyrimidinyl)-
- Sulfametoxydiazine
- Sulfanilamide, N(sup 1)-(5-methoxy-2-pyrimidinyl)-
Registry Numbers
CAS Registry Number
- 651-06-9
FDA UNII
- 3L179F09D6
System Generated Number
- 0000651069
Structure Descriptors
InChI
InChI=1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)InChIKey
GPTONYMQFTZPKC-UHFFFAOYSA-NSmiles
COc1cnc(NS(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LD50 | oral | 1gm/kg (1000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 695, 1961. | |
dog | LD50 | oral | 1gm/kg (1000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 695, 1961. | |
guinea pig | LD50 | oral | 2500mg/kg (2500mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 695, 1961. | |
mouse | LD50 | intraperitoneal | 3100mg/kg (3100mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 695, 1961. | |
mouse | LD50 | intravenous | 1gm/kg (1000mg/kg) | "Experimental Chemotherapy, Volume II," Schnitzer, R.J., and F. Hawking, eds. Academic Press New York, 1964Vol. 2, Pg. 249, 1964. | |
mouse | LD50 | oral | 16gm/kg (16000mg/kg) | Biochemical Pharmacology. Vol. 16, Pg. 1367, 1967. | |
mouse | LD50 | subcutaneous | 2500mg/kg (2500mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 695, 1961. | |
rabbit | LD50 | intravenous | 100mg/kg (100mg/kg) | "Experimental Chemotherapy, Volume II," Schnitzer, R.J., and F. Hawking, eds. Academic Press New York, 1964Vol. 2, Pg. 249, 1964. | |
rat | LD50 | intraperitoneal | 2300mg/kg (2300mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 695, 1961. | |
rat | LD50 | intravenous | 1gm/kg (1000mg/kg) | "Experimental Chemotherapy, Volume II," Schnitzer, R.J., and F. Hawking, eds. Academic Press New York, 1964Vol. 2, Pg. 249, 1964. | |
rat | LD50 | oral | 6gm/kg (6000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 695, 1961. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 214-216 | deg C | EXP | |
log P (octanol-water) | 0.41 | (none) | EXP | |
Water Solubility | 730 | mg/L | 30 | EXP |
Vapor Pressure | 8.35E-09 | mm Hg | 25 | EST |
Henry's Law Constant | 9.36E-12 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 2.80E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.