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Substance Name: Mapatumumab [USAN:INN]
RN: 658052-09-6
UNII: WZ1025JPGR

Note

  • A fully human IgG1 agonistic mAb that exclusively targets tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R1) which is overexpressed on the surface of many tumors.

Molecular Formula

  • C6388-H9856-N1712-O1998-S46
 

Classification Codes

  • Antineoplastic Agents
  • Treatment of Cancer
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Links to Resources

Names and Synonyms

Name of Substance

  • Mapatumumab
  • Mapatumumab [USAN:INN]

Synonyms

  • HGS-ETR1
  • Immunoglobulin G1, anti-(human cytokine receptor DR4 (death receceptor 4)) (human monoclonal TRM-1 heavy chain), disulfide with human monoclonal TRM-1 lambda-chain, dimer
  • Immunoglobulin G1, anti-(human TRAIL-R1) (human monoclonal TRM-1 heavy chain), disulfide with human monoclonal TRM-1 lambda-chain, dimer
  • Mapatumuma
  • Mapatumumab
  • TRAIL-R1 mAb
  • TRM-1
  • UNII-WZ1025JPGR

Registry Numbers

CAS Registry Number

  • 658052-09-6

FDA UNII

  • WZ1025JPGR

System Generated Number

  • 0658052096