Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Dienogest [USAN:INN:BAN]
RN: 65928-58-7
UNII: 46M3EV8HHE
InChIKey: AZFLJNIPTRTECV-FUMNGEBKSA-N

Molecular Formula

  • C20-H25-N-O2

Molecular Weight

  • 311.4225
 

Classification Codes

  • Antineoplastic Agents
  • Antineoplastic Agents, Hormonal
  • Contraceptive Agents
  • Contraceptive Agents, Female
  • Contraceptive Agents, Male
  • Contraceptives, Oral
  • Hormone
  • Hormone Antagonists
  • Hormone Replacement Therapy
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Mutation Data
  • Oral Contraceptive
  • Reproductive Control Agents
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Dienogest
  • Dienogest [USAN:INN:BAN]

Synonyms

  • 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one
  • 17-alpha-Cyanomethyl-17-beta-hydroxyestra-4,9(10)-diene-3-one
  • 17alpha-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile
  • 19-Norpregna-4,9-diene-21-nitrile, 17-hydroxy-3-oxo-, (17alpha)-
  • BAY 86-5258
  • BAY86-5258
  • Dienogest
  • Dienogestril
  • Dienogestum
  • Dienogestum [Latin]
  • Dinagest
  • Endometrion
  • M 18575
  • MJR-35
  • STS 557
  • UNII-46M3EV8HHE
  • Visanne
  • ZK 37659

Systematic Names

  • 17-Hydroxy-3-oxo-19-nor-17alpha-pregna-4,9-diene-21-nitrile
  • 19-Norpregna-4,9-diene-21-nitrile, 17-hydroxy-3-oxo-, (17-alpha)-

Registry Numbers

CAS Registry Number

  • 65928-58-7

FDA UNII

  • 46M3EV8HHE

System Generated Number

  • 0065928587

Structure Descriptors

InChI

1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1

InChIKey

AZFLJNIPTRTECV-FUMNGEBKSA-N

Smiles

C[C@]12CCC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@]2(O)CC#N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 4gm/kg (4000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Pharmazie. Vol. 34, Pg. 319, 1979.
mouse LDLo intraperitoneal 1gm/kg (1000mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Experimental and Clinical Edocrinology. Vol. 81, Pg. 175, 1983.
mouse LDLo subcutaneous 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Pharmazie. Vol. 34, Pg. 319, 1979.
rabbit LDLo intraperitoneal 1500mg/kg (1500mg/kg) ENDOCRINE: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Experimental and Clinical Edocrinology. Vol. 81, Pg. 175, 1983.
rabbit LDLo oral 1gm/kg (1000mg/kg)   Experimental and Clinical Edocrinology. Vol. 81, Pg. 175, 1983.
rabbit LDLo oral 1gm/kg (1000mg/kg) ENDOCRINE: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Experimental and Clinical Edocrinology. Vol. 81, Pg. 175, 1983.