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Substance Name: Uracil [USAN:JAN]
RN: 66-22-8
UNII: 56HH86ZVCT
InChIKey: ISAKRJDGNUQOIC-UHFFFAOYSA-N
Note
- One of four nucleotide bases in the nucleic acid RNA.
Molecular Formula
- C4-H4-N2-O2
Molecular Weight
- 112.0876
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Antineoplastic (Adjunct)
- Mutation Data
- Reproductive Effect
- Tumor Data
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Names and Synonyms
Name of Substance
- Uracil
- Uracil [USAN:JAN]
MeSH Heading
- Uracil
Synonyms
- 2,4-Dihydroxypyrimidine
- 2,4-Dioxopyrimidine
- 2,4-Pyrimidinediol
- 2,4-Pyrimidinedione
- AI3-25470
- BMS 205603-01
- BMS-205603-01
- CCRIS 3077
- EINECS 200-621-9
- Hybar X
- NSC 3970
- Pirod
- Pyrod
- RU 12709
- SQ 6201
- SQ 7726
- SQ 8493
- SQ-6201
- SQ-7726
- SQ-8493
- UNII-56HH86ZVCT
- Ura
- Uracil
Systematic Names
- 2,4(1H,3H)-Pyrimidinedione
- Uracil
Registry Numbers
CAS Registry Number
- 66-22-8
FDA UNII
- 56HH86ZVCT
Other Registry Numbers
- 138285-60-6
- 144104-68-7
- 153445-42-2
- 42910-77-0
- 4433-21-0
- 4433-24-3
- 51953-19-6
- 766-19-8
System Generated Number
- 0000066228
Structure Descriptors
InChI
1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)InChIKey
ISAKRJDGNUQOIC-UHFFFAOYSA-NSmiles
c1c[nH]c(=O)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | oral | > 5gm/kg (5000mg/kg) | Medicamentos de Actualidad. Vol. 21, Pg. 125, 1985. | |
| mouse | LD50 | intraperitoneal | 1513mg/kg (1513mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 207, Pg. 504, 1978. |
| mouse | LD50 | oral | > 8gm/kg (8000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 20, Pg. 1009, 1980. | |
| rabbit | LD50 | oral | > 10gm/kg (10000mg/kg) | Medicamentos de Actualidad. Vol. 21, Pg. 125, 1985. | |
| rat | LD50 | oral | > 6gm/kg (6000mg/kg) | Medicamentos de Actualidad. Vol. 21, Pg. 125, 1985. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 338 | deg C | EXP | |
| pKa Dissociation Constant | 9.45 | (none) | EXP | |
| log P (octanol-water) | -1.07E+00 | (none) | EXP | |
| Water Solubility | 3600 | mg/L | 25 | EXP |
| Henry's Law Constant | 1.91E-09 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 8.77E-12 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.