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Substance Name: Tetraethylammonium
RN: 66-40-0
UNII: 5AV7G7EIEE
InChIKey: CBXCPBUEXACCNR-UHFFFAOYSA-N

Note

  • A potassium-selective ion channel blocker. (From J Gen Phys 1994;104(1):173-90)

Molecular Formula

  • C8-H20-N

Molecular Weight

  • 130.253
 

Classification Codes

  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Membrane Transport Modulators
  • Potassium Channel Blockers
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Names and Synonyms

Name of Substance

  • Tetraethylammonium

MeSH Heading

  • Tetraethylammonium

Synonyms

  • 4-04-00-00331 (Beilstein Handbook Reference)
  • BRN 1738225
  • N,N,N-Triethylethanaminium
  • Tetraethylammonium
  • Tetraetilammonio
  • Tetraetilammonio [Italian]
  • Tetramon
  • Tetrylammonium
  • UNII-5AV7G7EIEE

Systematic Names

  • Ammonium, tetraethyl-
  • Ethanaminium, N,N,N-triethyl- (9CI)

Registry Numbers

CAS Registry Number

  • 66-40-0

FDA UNII

  • 5AV7G7EIEE

Related Registry Numbers

  • 56-34-8 (chloride)
  • 68-05-3 (iodide)
  • 71-91-0 (bromide)
  • 77-98-5 (hydroxide)

System Generated Number

  • 0000066400

Structure Descriptors

InChI

1S/C8H20N/c1-5-9(6-2,7-3)8-4/h5-8H2,1-4H3/q+1

InChIKey

CBXCPBUEXACCNR-UHFFFAOYSA-N

Smiles

[N+](CC)(CC)(CC)CC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 55mg/kg (55mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES

VASCULAR: ACUTE ARTERIAL OCCLUSION

BLOOD: NORMOCYTIC ANEMIA
Farmaco, Edizione Scientifica. Vol. 10, Pg. 1027, 1955.
mouse LD50 intraperitoneal 60mg/kg (60mg/kg) VASCULAR: ACUTE ARTERIAL OCCLUSION

BLOOD: NORMOCYTIC ANEMIA

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Farmaco, Edizione Scientifica. Vol. 10, Pg. 1027, 1955.
mouse LD50 intravenous 36mg/kg (36mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Medicinal and Pharmaceutical Chemistry. Vol. 3, Pg. 167, 1961.
mouse LD50 oral > 2gm/kg (2000mg/kg)   Farmaco, Edizione Scientifica. Vol. 10, Pg. 1027, 1955.
mouse LD50 subcutaneous 180mg/kg (180mg/kg)   Farmakologiya i Toksikologiya Vol. 25, Pg. 163, 1962.
rabbit LD50 intravenous 72mg/kg (72mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES

BLOOD: NORMOCYTIC ANEMIA

VASCULAR: ACUTE ARTERIAL OCCLUSION
Farmaco, Edizione Scientifica. Vol. 10, Pg. 1027, 1955.
rat LD50 intraperitoneal 115mg/kg (115mg/kg) BLOOD: NORMOCYTIC ANEMIA

KIDNEY, URETER, AND BLADDER: OTHER CHANGES

VASCULAR: ACUTE ARTERIAL OCCLUSION
Farmaco, Edizione Scientifica. Vol. 10, Pg. 1027, 1955.
rat LD50 intravenous 63mg/kg (63mg/kg) VASCULAR: ACUTE ARTERIAL OCCLUSION

KIDNEY, URETER, AND BLADDER: OTHER CHANGES

BLOOD: NORMOCYTIC ANEMIA
Farmaco, Edizione Scientifica. Vol. 10, Pg. 1027, 1955.