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Substance Name: Alendronic acid [INN:BAN]
RN: 66376-36-1
UNII: X1J18R4W8P
InChIKey: OGSPWJRAVKPPFI-UHFFFAOYSA-N

Note

  • A nonhormonal medication for the treatment of postmenopausal osteoporosis in women. This drug builds healthy bone, restoring some of the bone loss as a result of osteoporosis.

Molecular Formula

  • C4-H13-N-O7-P2

Molecular Weight

  • 249.0947
 

Classification Codes

  • Bone Density Conservation Agents
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • Alendronate
  • Alendronic acid
  • Alendronic acid [INN:BAN]

MeSH Heading

  • Alendronate

Synonyms

  • (4-Amino-1-hydroxybutylidene)bisphosphonic acid
  • 4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid)
  • 4-Amino-1-hydroxybutylidene-1,1-bisphosphonate
  • Acide alendronique
  • Acide alendronique [INN-French]
  • Acido alendronico
  • Acido alendronico [INN-Spanish]
  • Acidum alendronicum
  • Acidum alendronicum [INN-Latin]
  • Alendronate
  • Alendronic acid
  • Arendal
  • HSDB 7990
  • MK 217
  • UNII-X1J18R4W8P

Systematic Names

  • (4-Amino-1-hydroxybutylidene)diphosphonic acid
  • Phosphonic acid, (4-amino-1-hydroxybutylidene)bis-

Registry Numbers

CAS Registry Number

  • 66376-36-1

FDA UNII

  • X1J18R4W8P

Related Registry Number

  • 121268-17-5 (mono-hydrochloride salt, trihydrate)

System Generated Number

  • 0066376361

Structure Descriptors

InChI

1S/C4H13NO7P2/c5-3-1-2-4(6,13(7,8)9)14(10,11)12/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12)

InChIKey

OGSPWJRAVKPPFI-UHFFFAOYSA-N

Smiles

C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 234 dec deg C   EXP
pKa Dissociation Constant 2.72 (none) 25 EXP
log P (octanol-water) -1.300 (none)   EST
Atmospheric OH Rate Constant 3.82E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.