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Substance Name: Pro-opiomelanocortin
RN: 66796-54-1

Note

  • A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
 
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Names and Synonyms

Name of Substance

  • Pro-opiomelanocortin

MeSH Heading

  • Pro-opiomelanocortin

Synonyms

  • POMC
  • Pro-opiocortin
  • Pro-opiomelanocortin

Systematic Name

  • Opiomelanocortin, pro-

Registry Numbers

CAS Registry Number

  • 66796-54-1

System Generated Number

  • 0066796541