Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Pro-opiomelanocortin
RN: 66796-54-1


  • A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)

Names and Synonyms

Name of Substance

  • Pro-opiomelanocortin

MeSH Heading

  • Pro-opiomelanocortin


  • POMC
  • Pro-opiocortin
  • Pro-opiomelanocortin

Systematic Name

  • Opiomelanocortin, pro-

Registry Numbers

CAS Registry Number

  • 66796-54-1

System Generated Number

  • 0066796541