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Substance Name: Halobetasol propionate [USAN:USP]
RN: 66852-54-8
UNII: 91A0K1TY3Z
InChIKey: BDSYKGHYMJNPAB-LICBFIPMSA-N
Note
- Used in ointment to treat psoriasis; Ulobetasol cream contains 0.05% 6-fluoroclobetasol 17-propionate
Molecular Formula
- C25-H31-Cl-F2-O5
Molecular Weight
- 484.9639
Classification Codes
- Anti-Inflammatory (Topical)
- Drug / Therapeutic Agent
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Names and Synonyms
Name of Substance
- Halobetasol
- Halobetasol propionate [USAN:USP]
Synonyms
- 21-Chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
- BMY 30056
- BMY-30056
- CGP 14458
- CGP-14,458
- Halobetasol propionate
- Ulobetasol propionate
- Ultravate
- UNII-91A0K1TY3Z
Systematic Name
- Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6alpha,11beta,16beta)-
Superlist Name
- Halobetasol propionate
Registry Numbers
CAS Registry Number
- 66852-54-8
FDA UNII
- 91A0K1TY3Z
System Generated Number
- 0066852548
Structure Descriptors
InChI
InChI=1S/C25H31ClF2O5/c1-5-21(32)33-25(20(31)12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15-,16-,18-,19-,22-,23-,24-,25-/m0/s1InChIKey
BDSYKGHYMJNPAB-LICBFIPMSA-NSmiles
CCC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
rat | LD50 | oral | > 15mL/kg (15mL/kg) | Medicamentos de Actualidad. Vol. 27, Pg. 304, 1991. |