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Substance Name: Egtazic acid [USAN:INN]
RN: 67-42-5
UNII: 526U7A2651
InChIKey: DEFVIWRASFVYLL-UHFFFAOYSA-N

Note

  • A chelating agent relatively more specific for calcium and less toxic than EDETIC ACID.

Molecular Formula

  • C14-H24-N2-O10

Molecular Weight

  • 380.348
 

Classification Codes

  • Antidotes
  • Calcium Chelating Agents
  • Chelating Agents
  • Pharmaceutic Aid
  • Protective Agents
  • Sequestering Agents
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Names and Synonyms

Name of Substance

  • Egtazic acid
  • Egtazic acid [USAN:INN]

MeSH Heading

  • Egtazic acid

Synonyms

  • (Ethylenebis(oxyethylenenitrilo))tetraacetic acid
  • 1,2-Bis(2-dicarboxymethylaminoethoxy)ethane
  • 4-04-00-02433 (Beilstein Handbook Reference)
  • Acide egtazique
  • Acide egtazique [INN-French]
  • Acido egtazico
  • Acido egtazico [INN-Spanish]
  • Acidum egtazicum
  • Acidum egtazicum [INN-Latin]
  • BRN 1717370
  • Ebonta
  • EGTA
  • Egtazic acid
  • EINECS 200-651-2
  • Ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid
  • Ethylene glycol bis(2-aminoethyl ether)tetraacetic acid
  • Ethylene glycol bis(aminoethyl ether)tetraacetate
  • Ethylene glycol bis(beta-aminoethyl ether)-N,N'-tetraacetic acid
  • Ethylene glycol, di(2-(N,N-dicarboxylmethyl)amino)ethyl ether
  • Ethylenebis(oxyethylenenitrilo)tetraacetic acid
  • Ethylenedioxybis(ethyleneamino)tetraacetic acid
  • Ethyleneglycol-bis(beta-aminoethyl ether)-N,N1-tetra-acetic acid
  • Gedta
  • Glycol-etherdiaminetetraacetic acid
  • NSC 615010
  • UNII-526U7A2651

Systematic Names

  • 6,9-Dioxa-3,12-diazatetradecanedioic acid, 3,12-bis(carboxymethyl)-
  • Acetic acid, (ethylenebis(oxyethylenenitrilo))tetra-
  • Ethylenebis(oxyethylenenitrilo)tetra(acetic acid)

Registry Numbers

CAS Registry Number

  • 67-42-5

FDA UNII

  • 526U7A2651

Other Registry Numbers

  • 33382-61-5
  • 56618-01-0

Related Registry Number

  • 31571-71-8 (hydrochloride salt)

System Generated Number

  • 0000067425

Structure Descriptors

InChI

1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)

InChIKey

DEFVIWRASFVYLL-UHFFFAOYSA-N

Smiles

OC(=O)CN(CCOCCOCCN(CC(O)=O)CC(=O)O)CC(O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 150mg/kg (150mg/kg)   National Technical Information Service. Vol. AD691-490,
rat LD50 oral 3587mg/kg (3587mg/kg)   Toxicology and Applied Pharmacology. Vol. 16, Pg. 807, 1970.