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Substance Name: Methyl alcohol [NF]
RN: 67-56-1
UNII: Y4S76JWI15
InChIKey: OKKJLVBELUTLKV-UHFFFAOYSA-N

Note

  • A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.

Molecular Formula

  • C-H4-O

Molecular Weight

  • 32.0416
 

Classification Codes

Classification Codes

  • Drug / Therapeutic Agent
  • Human Data
  • Mutation Data
  • Pharmaceutic Aid (Solvent)
  • Reproductive Effect
  • Skin / Eye Irritant
  • Solvents

Superlist Classification Codes

  • Reportable Quantity (RQ) = 5000 lb
  • TWA (200 ppm); STEL (250 ppm); skin; BEI
  • TWA 200 ppm (260 mg/m3)

Names and Synonyms

Name of Substance

  • Methanol
  • Methyl alcohol
  • Methyl alcohol [NF]

MeSH Heading

  • Methanol

Synonyms

  • AI3-00409
  • Alcohol, methyl
  • Alcool methylique
  • Alcool methylique [French]
  • Alcool metilico
  • Alcool metilico [Italian]
  • Bieleski's solution
  • Carbinol
  • Caswell No. 552
  • CCRIS 2301
  • Coat-B1400
  • Colonial Spirit
  • Colonial spirits
  • Columbian Spirit
  • Columbian spirits
  • EC 200-659-6
  • EINECS 200-659-6
  • EPA Pesticide Chemical Code 053801
  • Eureka Products Criosine Disinfectant
  • Eureka Products, Criosine
  • Freers Elm Arrester
  • HSDB 93
  • Ideal Concentrated Wood Preservative
  • Metanol
  • Metanol [Spanish]
  • Metanolo
  • Metanolo [Italian]
  • Methanol
  • Methyl alcohol
  • Methyl hydrate
  • Methyl hydroxide
  • Methylalkohol
  • Methylalkohol [German]
  • Methylol
  • Metylowy alkohol
  • Metylowy alkohol [Polish]
  • Monohydroxymethane
  • NSC 85232
  • Pyroxylic Spirit
  • Pyroxylic spirits
  • RCRA waste number U154
  • Surflo-B17
  • UNII-Y4S76JWI15
  • Wilbur-Ellis Smut-Guard
  • Wood alcohol
  • Wood naphtha
  • Wood Spirit
  • X-Cide 402 Industrial Bactericide

Systematic Name

  • Methanol

Superlist Names

  • Methanol
  • Methanol, or methyl alcohol
  • Methanol, or methyl alcohol [UN1230] [Flammable liquid, Poison]
  • Methyl alcohol
  • RCRA waste no. U154
  • UN1230

Registry Numbers

CAS Registry Number

  • 67-56-1

FDA UNII

  • Y4S76JWI15

Other Registry Numbers

  • 1173023-83-0
  • 54841-71-3

System Generated Number

  • 0000067561

Structure Descriptors

InChI

1S/CH4O/c1-2/h2H,1H3

InChIKey

OKKJLVBELUTLKV-UHFFFAOYSA-N

Smiles

CO

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LCLo inhalation 44gm/m3/6H (44000mg/m3) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: MUSCLE WEAKNESS
Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
cat LDLo intravenous 4641mg/kg (4641mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 16, Pg. 1, 1920.
dog LDLo oral 7500mg/kg (7500mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1365, 1935.
frog LDLo parenteral 59gm/kg (59000mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 296, 1935.
guinea pig LD50 intraperitoneal 3556mg/kg (3556mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
hamster LD50 intraperitoneal 8555mg/kg (8555mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
human LDLo oral 143mg/kg (143mg/kg) SENSE ORGANS AND SPECIAL SENSES: OPTIC NERVE NEUROPATHY: EYE

GASTROINTESTINAL: NAUSEA OR VOMITING

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 382, 1969.
human LDLo oral 428mg/kg (428mg/kg) BEHAVIORAL: HEADACHE

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 74, 1974.
human TCLo inhalation 300ppm (300ppm) BEHAVIORAL: HEADACHE

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE
Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 74, 1974.
human TCLo inhalation 86000mg/m3 (86000mg/m3) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

LUNGS, THORAX, OR RESPIRATION: COUGH

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
man LDLo oral 6422mg/kg (6422mg/kg) BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)"

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: NAUSEA OR VOMITING
Canadian Medical Association Journal. Vol. 128, Pg. 14, 1983.
man LDLo unreported 868mg/kg (868mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man TDLo oral 3571uL/kg (3.571mL/kg) BLOOD: OTHER CHANGES

SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 35, Pg. 2095, 1993.
man TDLo oral 9450uL/kg (9.45mL/kg)   American Journal of Emergency Medicine. Vol. 16, Pg. 538, 1998.
man TDLo oral 9450uL/kg (9.45mL/kg) BEHAVIORAL: GENERAL ANESTHETIC

SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
American Journal of Emergency Medicine. Vol. 16, Pg. 538, 1998.
man TDLo oral 3429mg/kg (3429mg/kg) SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE Acta Medica Scandinavica. Vol. 212, Pg. 5, 1982.
monkey LCLo inhalation 1000ppm (1000ppm)   Industrial and Engineering Chemistry. Vol. 23, Pg. 931, 1931.
monkey LD50 oral 7gm/kg (7000mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: ATAXIA

BEHAVIORAL: COMA
Toxicology and Applied Pharmacology. Vol. 3, Pg. 202, 1961.
monkey LDLo skin 393mg/kg (393mg/kg)   Industrial and Engineering Chemistry. Vol. 23, Pg. 931, 1931.
mouse LCLo inhalation 50gm/m3/2H (50000mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 80, 1982.
mouse LD50 intraperitoneal 10765mg/kg (10765mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
mouse LD50 intravenous 4710mg/kg (4710mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
mouse LD50 oral 7300mg/kg (7300mg/kg)   Toxicology. Vol. 25, Pg. 271, 1982.
mouse LD50 subcutaneous 9800mg/kg (9800mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rabbit LD50 intraperitoneal 1826mg/kg (1826mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rabbit LD50 intravenous 8907mg/kg (8907mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rabbit LD50 oral 14200mg/kg (14200mg/kg)   FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 105, 1970.
rabbit LD50 skin 15800mg/kg (15800mg/kg)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 74, 1974.
rat LC50 inhalation 64000ppm/4H (64000ppm)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 74, 1974.
rat LD50 intraperitoneal 7529mg/kg (7529mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rat LD50 intravenous 2131mg/kg (2131mg/kg)   EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985.
rat LD50 oral 5628mg/kg (5628mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(11), Pg. 27, 1975.
women TDLo oral 4gm/kg (4000mg/kg) SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE

GASTROINTESTINAL: NAUSEA OR VOMITING

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Acta Medica Scandinavica. Vol. 212, Pg. 5, 1982.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -9.76E+01 deg C   EXP
Boiling Point 64.6 deg C   EXP
pKa Dissociation Constant 15.3 (none)   EXP
log P (octanol-water) -0.77 (none)   EXP
Water Solubility 1.00E+06 mg/L 25 EXP
Vapor Pressure 127 mm Hg 25 EXP
Henry's Law Constant 4.55E-06 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 9.44E-13 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.