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Substance Name: Isopropyl alcohol [USP]
RN: 67-63-0
UNII: ND2M416302
InChIKey: KFZMGEQAYNKOFK-UHFFFAOYSA-N
Note
- An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Molecular Formula
- C3-H8-O
Molecular Weight
- 60.0952
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Agricultural Chemical
- Anti-Infective, Topical
- Drug / Therapeutic Agent
- Fungicide, Bactericide, Wood Preservative
- Human Data
- Mutation Data
- Pharmaceutic Aid (Solvent)
- Reproductive Effect
- Skin / Eye Irritant
- Slimicide
- Solvents
- Tumor Data
Superlist Classification Codes
- Overall Carcinogenic Evaluation: Group 3
- TWA (200 ppm); STEL (400 ppm); Not classifiable as a human carcinogen
- TWA 400 ppm (980 mg/m3)
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Names and Synonyms
Name of Substance
- 2-Propanol
- Isopropanol
- Isopropyl alcohol [USP]
MeSH Heading
- 2-Propanol
Synonyms
- 1-Methylethanol
- 1-Methylethyl alcohol
- 2-Hydroxypropane
- 2-Propanol
- 2-Propyl alcohol
- 4-01-00-01461 (Beilstein Handbook Reference)
- AI3-01636
- Alcojel
- Alcolo
- Alcool isopropilico
- Alcool isopropilico [Italian]
- Alcool isopropylique
- Alcool isopropylique [French]
- Alcosolve
- Alcosolve 2
- Alkolave
- Arquad DMCB
- Avantin
- Avantine
- BRN 0635639
- Caswell No. 507
- CCRIS 2308
- Combi-schutz
- Dimethylcarbinol
- EC 200-661-7
- EINECS 200-661-7
- EPA Pesticide Chemical Code 047601
- FEMA No. 2929
- FEMA Number 2929
- Hartosol
- HSDB 116
- i-Propanol
- i-Propanol [German]
- i-Propyl alcohol
- i-Propylalkohol
- i-Propylalkohol [German]
- Imsol A
- Iso-propylalkohol
- Iso-propylalkohol [German]
- Isohol
- Isopropanol
- Isopropyl alcohol
- Isopropyl alcohol, rubbing
- Lavacol
- Lutosol
- n-Propan-2-ol
- NSC 135801
- Petrohol
- Propol
- sec-Propyl alcohol
- Spectrar
- Sterisol hand disinfectant
- Takineocol
- UNII-ND2M416302
- Visco 1152
Systematic Names
- 2-Propanol
- Isopropyl alcohol
- Propan-2-ol
Superlist Names
- 2-Propanol
- Iso-propyl alcohol
- Isopropanol
- Isopropanol or isopropyl alcohol
- Isopropanol or isopropyl alcohol [UN1219] [Flammable liquid]
- Isopropyl alcohol
- Isopropyl alcohol (manufacture strong-acid process)
- Isopropyl alcohol (manufacturing-strong acid process only)
- Isopropyl alcohol (only persons who manufacture by the strong acid process are subject, supplier notification not required)
- UN1219
Mixture Name
- Hibistat
Registry Numbers
CAS Registry Number
- 67-63-0
FDA UNII
- ND2M416302
Other Registry Number
- 8013-70-5
System Generated Number
- 0000067630
Structure Descriptors
InChI
1S/C3H8O/c1-3(2)4/h3-4H,1-2H3InChIKey
KFZMGEQAYNKOFK-UHFFFAOYSA-NSmiles
C(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | intravenous | 1963mg/kg (1963mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 172, 1955. | |
cat | LDLo | oral | 6mL/kg (6mL/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 26, Pg. 285, 1921. | |
dog | LDLo | intravenous | 1024mg/kg (1024mg/kg) | Journal of Laboratory and Clinical Medicine. Vol. 29, Pg. 561, 1944. | |
dog | LDLo | oral | 1537mg/kg (1537mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING | Journal of Laboratory and Clinical Medicine. Vol. 29, Pg. 561, 1944. |
frog | LDLo | parenteral | 20gm/kg (20000mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 296, 1935. |
guinea pig | LD50 | intraperitoneal | 2560mg/kg (2560mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
hamster | LD50 | intraperitoneal | 3444mg/kg (3444mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
human | LDLo | oral | 3570mg/kg (3570mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: COMA | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 339, 1969. |
human | LDLo | unreported | 2mL/kg (2mL/kg) | Japanese Journal of Toxicology. Vol. 12, Pg. 341, 1999. | |
human | TDLo | oral | 223mg/kg (223mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION CARDIAC: PULSE RATE BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" | Journal of Laboratory and Clinical Medicine. Vol. 12, Pg. 326, 1927. |
infant | TDLo | oral | 13gm/kg (13000mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: IRRITABILITY BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | American Journal of Emergency Medicine. Vol. 10, Pg. 542, 1992. |
infant | TDLo | unreported | 1375mg/kg (1375mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Pediatric Emergency Care. Vol. 9, Pg. 146, 1993. |
mammal (species unspecified) | LDLo | subcutaneous | 6gm/kg (6000mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: GENERAL ANESTHETIC PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE | Archiv fuer Toxikologie. Vol. 16, Pg. 84, 1956. |
man | LDLo | oral | 5272mg/kg (5272mg/kg) | LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA BEHAVIORAL: COMA VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION | American Journal of Clinical Pathology. Vol. 38, Pg. 144, 1962. |
man | LDLo | unreported | 2770mg/kg (2770mg/kg) | "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. | |
man | TDLo | oral | 14432mg/kg (14432mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: COMA VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION | New England Journal of Medicine. Vol. 277, Pg. 699, 1967. |
mouse | LCLo | inhalation | 12800ppm/3H (12800ppm) | Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974, | |
mouse | LD50 | intraperitoneal | 4477mg/kg (4477mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
mouse | LD50 | intravenous | 1509mg/kg (1509mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
mouse | LD50 | oral | 3600mg/kg (3600mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 43(1), Pg. 8, 1978. |
mouse | LDLo | subcutaneous | 6gm/kg (6000mg/kg) | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 172, 1955. | |
rabbit | LD50 | intraperitoneal | 667mg/kg (667mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
rabbit | LD50 | intravenous | 1184mg/kg (1184mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
rabbit | LD50 | oral | 6410mg/kg (6410mg/kg) | FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 114, 1970. | |
rabbit | LD50 | skin | 12800mg/kg (12800mg/kg) | Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 100, 1974. | |
rat | LC50 | inhalation | 16000ppm/8H (16000ppm) | Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 100, 1974. | |
rat | LD50 | intraperitoneal | 2735mg/kg (2735mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
rat | LD50 | intravenous | 1088mg/kg (1088mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
rat | LD50 | oral | 5045mg/kg (5045mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 43(1), Pg. 8, 1978. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | -8.95E+01 | deg C | EXP | |
Boiling Point | 82.3 | deg C | EXP | |
pKa Dissociation Constant | 17.1 | (none) | EXP | |
log P (octanol-water) | 0.05 | (none) | EXP | |
Water Solubility | 1.00E+06 | mg/L | 25 | EXP |
Vapor Pressure | 45.4 | mm Hg | 25 | EXP |
Henry's Law Constant | 8.10E-06 | atm-m3/mole | 25 | EXP |
Atmospheric OH Rate Constant | 5.07E-12 | cm3/molecule-sec | 25 | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.