Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Mildiomycin
RN: 67527-71-3
UNII: WPS3TSW377
InChIKey: QKJJCZYFXJCKRX-HZHKWBLPSA-N

Note

  • Antibiotic nucleoside produced by Streptoverticillium rimofaciens effective against powdery mildew; 5-hydroxymethyl cytosine found on acid hydrolysis.

Molecular Formulas

  • C19-H30-N8-O9
  • C19-H30-N8-O9.H2-O

Molecular Weight

  • 514.493
 

Classification Codes

  • Drug / Therapeutic Agent
  • Natural Product
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Mildiomycin

Synonyms

  • Antibiotic B-98891
  • B-98891
  • MIL
  • UNII-WPS3TSW377

Systematic Names

  • 2(1H)-Pyrimidinone, 4-amino-1-(4-((2-amino-3-hydroxy-1-oxopropyl)amino)-9-((aminoiminomethyl)amino)-6-C-carboxy-2,3,4,7,9-pentadeoxy-alpha-L-talo-non-2-enopyranosyl)-5-(hydroxymethyl)-, (S)-
  • Mildiomycin

Registry Numbers

CAS Registry Number

  • 67527-71-3

FDA UNII

  • WPS3TSW377

System Generated Number

  • 0067527713

Molecular Formulas

Molecular Formulas

  • C19-H30-N8-O9
  • C19-H30-N8-O9.H2-O

Molecular Formula Fragments

  • C19-H30-N8-O9
  • COMPONENT
  • H2-O

Structure Descriptors

InChI

1S/C19H30N8O9/c20-10(7-29)15(31)25-11-1-2-12(27-5-8(6-28)14(21)26-18(27)34)36-13(11)19(35,16(32)33)3-9(30)4-24-17(22)23/h1-2,5,9-13,28-30,35H,3-4,6-7,20H2,(H,25,31)(H,32,33)(H2,21,26,34)(H4,22,23,24)/t9?,10-,11-,12+,13-,19?/m0/s1

InChIKey

QKJJCZYFXJCKRX-HZHKWBLPSA-N

Smiles

N[C@@H](CO)C(=O)N[C@H]1C=C[C@@H](O[C@@H]1C(O)(CC(O)CN=C(N)N)C(=O)O)N2C=C(CO)C(=NC2=O)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1020mg/kg (1020mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 19, Pg. S135, 1994.
mouse LD50 intravenous 500mg/kg (500mg/kg)   Journal of Antibiotics. Vol. 31, Pg. 519, 1978.
mouse LD50 oral 2500mg/kg (2500mg/kg)   Journal of Antibiotics. Vol. 31, Pg. 519, 1978.
mouse LD50 skin > 5gm/kg (5000mg/kg)   Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 19, Pg. S135, 1994.
mouse LD50 subcutaneous 500mg/kg (500mg/kg)   Journal of Antibiotics. Vol. 31, Pg. 519, 1978.
rat LC50 inhalation 880mg/m3/4H (880mg/m3)   Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 19, Pg. S135, 1994.
rat LD50 intraperitoneal 679mg/kg (679mg/kg)   Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 19, Pg. S135, 1994.
rat LD50 intravenous 500mg/kg (500mg/kg)   Journal of Antibiotics. Vol. 31, Pg. 519, 1978.
rat LD50 oral 2500mg/kg (2500mg/kg)   Journal of Antibiotics. Vol. 31, Pg. 519, 1978.
rat LD50 skin > 5gm/kg (5000mg/kg)   Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 19, Pg. S135, 1994.
rat LD50 subcutaneous 500mg/kg (500mg/kg)   Journal of Antibiotics. Vol. 31, Pg. 519, 1978.