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Substance Name: Methoxy polyethylene glycol-epoetin beta
RN: 677324-53-7


  • A third-generation erythropoietic beta molecule created by integrating a large polymer chain into the molecule, thus increasing the molecular weight to twice that of epoetin at approximately 60 kDa; the methoxy-polyethylene glycol polymer chain is integrated via amide bonds between the N-terminal amino group or the e-amino group of lysine (predominantly lysine-52 or lysine-45), using a single succinimidyl butanoic acid linker; an erythropoiesis-stimulating agent for the treatment of anemia.
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Names and Synonyms

Name of Substance

  • Methoxy polyethylene glycol-epoetin beta


  • 1-165-Erythropoietin (human), monamide with alpha-(3-carboxypropyl)-omega-methoxypoly(oxy-1,2-ethanediyl)
  • CERA
  • Continuous erythropoietin receptor activator
  • HSDB 8219
  • Methoxy polyethylene glycol-epoetinbeta [EMA EPAR]
  • Methoxy polyethylene glycol-epoetinbeta [MART.]
  • Mircera
  • Pegzerepoetin alfa
  • Pegzerepoetin alfa [WHO-DD]
  • UNII-LR3UXN0193

Registry Numbers

CAS Registry Number

  • 677324-53-7


  • LR3UXN0193

Other Registry Number

  • 917756-28-6

System Generated Number

  • 0677324537