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Substance Name: Hydroxyprogesterone [INN:BAN]
RN: 68-96-2
UNII: 21807M87J2
InChIKey: DBPWSSGDRRHUNT-CEGNMAFCSA-N

Note

  • A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES.

Molecular Formula

  • C21-H30-O3

Molecular Weight

  • 330.465
 

Classification Codes

  • Hormone
  • Human Data
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • 17-Hydroxyprogesterone
  • 17alpha-Hydroxyprogesterone
  • Hydroxyprogesterone [INN:BAN]

MeSH Heading

  • 17-alpha-Hydroxyprogesterone

Synonyms

  • 17-Hydroxypregn-4-ene-3,20-dione
  • 17-Hydroxyprogesterone
  • 4-08-00-02189 (Beilstein Handbook Reference)
  • alpha Hydroxy progesterone
  • BRN 2062088
  • delta(4)-Pregnene-17alpha-ol-3,20-dione
  • EINECS 200-699-4
  • Gestageno gador
  • Hidroxiprogesterona
  • Hidroxiprogesterona [INN-Spanish]
  • HSDB 3343
  • Hydroxyprogesterone
  • Hydroxyprogesteronum
  • Hydroxyprogesteronum [INN-Latin]
  • Idrossiprogesterone
  • Idrossiprogesterone [DCIT]
  • NSC 15468
  • Oxiprogesteronum
  • Pregn-4-ene-3,20-dione, 17-hydroxy-
  • Prodix
  • Prodox
  • Proluton
  • Setaderm
  • U 3096
  • UNII-21807M87J2

Systematic Names

  • Hydroxyprogesterone
  • Pregn-4-ene-3,20-dione, 17-hydroxy-

Registry Numbers

CAS Registry Number

  • 68-96-2

FDA UNII

  • 21807M87J2

Other Registry Numbers

  • 1050677-68-3
  • 67085-08-9

System Generated Number

  • 0000068962

Structure Descriptors

InChI

1S/C21H30O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h12,16-18,24H,4-11H2,1-3H3/t16-,17+,18+,19+,20+,21+/m1/s1

InChIKey

DBPWSSGDRRHUNT-CEGNMAFCSA-N

Smiles

CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 222-223 deg C   EXP
log P (octanol-water) 3.17 (none)   EXP
Water Solubility 6.48 mg/L 27 EXP
Vapor Pressure 9.28E-10 mm Hg 25 EST
Henry's Law Constant 1.01E-08 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.03E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.