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Substance Name: Ibalizumab [USAN:INN]
RN: 680188-33-4
UNII: LT369U66CE

Note

  • A monoclonal antibody, TNX-355, prevents entry of human immunodeficiency virus (HIV) into the host cell. TNX-355 binds to the CD4 receptor on the cell's surface, an entry gate for infection, preventing viral entry and thereby blocking infection.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Anti-HIV Agents
  • Anti-Infective Agents
  • Anti-Retroviral Agents
  • Antiviral Agents
  • Treatment of HIV/AIDS in HIV-1 Infected Patients
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Links to Resources

Names and Synonyms

Name of Substance

  • Ibalizumab [USAN:INN]

Synonyms

  • Hu-5A8
  • Hu5A8
  • Ibalizumab
  • TMB 355
  • TMB-355
  • TMB355
  • TNX 355
  • TNX-355
  • UNII-LT369U66CE

Systematic Name

  • Immunoglobulin G4, anti-(human CD4 (antigen)) (human-mouse monoclonal 5A8 gamma4-chain), disulfide with human-mouse monoclonal 5A8 kappa-chain, dimer

Registry Numbers

CAS Registry Number

  • 680188-33-4

FDA UNII

  • LT369U66CE

Other Registry Number

  • 872357-57-8

System Generated Number

  • 0680188334