Skip Navigation
ChemIDplus LiteBrowseAdvanced

Substance Name: Levoleucovorin
RN: 68538-85-2
UNII: 990S25980Y
InChIKey: VVIAGPKUTFNRDU-STQMWFEESA-N

Note

  • A folate analog consisting of the pharmacologically active isomer of LEUCOVORIN.

Classification Codes

  • Antidotes
  • Protective Agents

Molecular Formula

  • C20-H23-N7-O7

Molecular Weight

  • 473.4437
 

Names and Synonyms

Results Name

  • Levoleucovorin

Name of Substance

  • Levoleucovorin

MeSH Heading

  • Levoleucovorin

Synonyms

  • (6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid
  • (6S)-Folinic acid
  • (6S)-Leucovorin
  • (S)-Leucovorin
  • Citrovorum factor
  • L-Folinic acid
  • levo-Folinic
  • Levofolene
  • Levofolinic acid
  • LFP 754
  • UNII-990S25980Y

Systematic Names

  • L-Glutamic acid, N-(4-((((6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-
  • L-Glutamic acid, N-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, (S)-

Registry Numbers

CAS Registry Number

  • 68538-85-2

FDA UNII

  • 990S25980Y

Other Registry Numbers

  • 121451-09-0
  • 51057-63-7

System Generated Number

  • 0068538852

Structure Descriptors

InChI

InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13-/m0/s1

InChIKey

VVIAGPKUTFNRDU-STQMWFEESA-N

Smiles

NC1=NC(=O)C2=C(NC[C@H](CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)N2C=O)N1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo intraperitoneal 1gm/kg (1000mg/kg)   Annals of the New York Academy of Sciences. Vol. 60, Pg. 251, 1954.