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Substance Name: Lorapride [INN]
RN: 68677-06-5
UNII: 549TIC7B4R
InChIKey: YSWVLPFCGJOQQA-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C14-H22-Cl-N3-O3-S

Molecular Weight

  • 347.865
 
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Names and Synonyms

Name of Substance

  • Lorapride
  • Lorapride [INN]

Synonyms

  • 4-Amino-5-chloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzenesulfonamide
  • 5-Chloro-N(sup 1)-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxysulfanilamide
  • BRN 0441632
  • EINECS 272-057-1
  • Loraprida
  • Loraprida [INN-Spanish]
  • Lorapride
  • Lorapridum
  • Lorapridum [INN-Latin]
  • UNII-549TIC7B4R

Systematic Names

  • 5-Chloro-N(sup 1)-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxysulfanilamide
  • Benzenesulfonamide, 4-amino-5-chloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-
  • Lorapride

Registry Numbers

CAS Registry Number

  • 68677-06-5

FDA UNII

  • 549TIC7B4R

System Generated Number

  • 0068677065

Structure Descriptors

InChI

1S/C14H22ClN3O3S/c1-3-18-6-4-5-10(18)9-17-22(19,20)14-7-11(15)12(16)8-13(14)21-2/h7-8,10,17H,3-6,9,16H2,1-2H3

InChIKey

YSWVLPFCGJOQQA-UHFFFAOYSA-N

Smiles

C1C[C@@H](CNS(c2cc(c(cc2OC)N)Cl)(=O)=O)[N@@](CC)C1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 130mg/kg (130mg/kg)   United States Patent Document. Vol. #4225611,
mouse LD50 oral 1gm/kg (1000mg/kg)   United States Patent Document. Vol. #4225611,
rat LD50 oral 1500mg/kg (1500mg/kg)   United States Patent Document. Vol. #4225611,