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Substance Name: Lipofundin S
RN: 68890-65-3
InChIKey: ZACMUBKIFQNSDT-GAUHYDFOSA-O

Note

  • Emulsion containing soy bean oil, soy phosphatides & glycerol.

Molecular Weight

  • 1041.5395
 
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Names and Synonyms

Name of Substance

  • Lipofundin S

Synonyms

  • Intralipid
  • Intralipid 20
  • Lipofundin S
  • Lipofundin S 10
  • Medialipid
  • Phospholipid - stabilized soybean oil
  • Salvilipid
  • Travamulsion

Systematic Name

  • Soybean oil, phospholipid-stabilized

Registry Numbers

CAS Registry Number

  • 68890-65-3

Other Registry Numbers

  • 11116-61-3
  • 53529-18-3
  • 53637-06-2

System Generated Number

  • 0068890653

Structure Descriptors

InChI

1S/C42H82NO8P.C18H32O2/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h20-21,40H,6-19,22-39H2,1-5H3;6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/p+1/b21-20+;7-6-,10-9-

InChIKey

ZACMUBKIFQNSDT-GAUHYDFOSA-O

Smiles

CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C\CCCCCCCC.CCCCC\C=C/C\C=C/CCCCCCCC(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 parenteral 120mL/kg (120mL/kg)   United States Patent Document. Vol. #5439686,
pig LDLo intravenous 6gm/kg (6000mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 1472, 1965.
rat LD50 intravenous 150gm/kg (150000mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 6, Pg. 3567, 1978.