Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Eledoisin [INN]
RN: 69-25-0
UNII: OKY3285J18
InChIKey: AYLPVIWBPZMVSH-FCKMLYJASA-N

Note

  • A peptide extracted from the posterior salivary glands of certain small octopi (Eledone spp., Mollusca), or obtained by synthesis. Its actions resemble those of SUBSTANCE P; it is a potent vasodilator and increases capillary permeability. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1364)

Molecular Formula

  • C54-H85-N13-O15-S

Molecular Weight

  • 1188.4075
 

Classification Codes

  • Natural Product
  • Neurotransmitter Agents
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Eledoisin
  • Eledoisin [INN]

MeSH Heading

  • Eledoisin

Synonyms

  • BRN 4796573
  • ELD 950
  • Eledoisin
  • Eledoisina
  • Eledoisina [INN-Spanish]
  • Eledoisine
  • Eledoisine [INN-French]
  • Eledoisinum
  • Eledone peptide
  • FI 6225 TF/Ocoa
  • UNII-OKY3285J18

Systematic Names

  • 5-Oxo-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-L-methioninamide
  • Eledoisin

Registry Numbers

CAS Registry Number

  • 69-25-0

FDA UNII

  • OKY3285J18

System Generated Number

  • 0000069250

Structure Descriptors

InChI

1S/C54H85N13O15S/c1-7-30(4)44(53(81)57-27-42(70)60-36(24-29(2)3)49(77)61-33(45(56)73)20-23-83-6)66-50(78)37(25-32-14-9-8-10-15-32)63-46(74)31(5)58-48(76)38(26-43(71)72)64-47(75)34(16-11-12-21-55)62-51(79)39(28-68)65-52(80)40-17-13-22-67(40)54(82)35-18-19-41(69)59-35/h8-10,14-15,29-31,33-40,44,68H,7,11-13,16-28,55H2,1-6H3,(H2,56,73)(H,57,81)(H,58,76)(H,59,69)(H,60,70)(H,61,77)(H,62,79)(H,63,74)(H,64,75)(H,65,80)(H,66,78)(H,71,72)/t30-,31-,33-,34-,35-,36-,37-,38-,39-,40-,44-/m0/s1

InChIKey

AYLPVIWBPZMVSH-FCKMLYJASA-N

Smiles

CC[C@H](C)[C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCC(=O)N3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo subcutaneous 300ug/kg (0.3mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

CARDIAC: OTHER CHANGES
Experientia. Vol. 18, Pg. 58, 1962.