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Substance Name: Alfentanil hydrochloride [USAN]
RN: 69049-06-5
UNII: 333JTI7A2M
InChIKey: AQORHZJDCHLLJN-UHFFFAOYSA-N
Note
- A short-acting opioid anesthetic and analgesic derivative of FENTANYL. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Molecular Formula
- C21-H32-N6-O3.Cl-H
Molecular Weight
- 452.9837
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Names and Synonyms
Name of Substance
- Alfentanil hydrochloride
- Alfentanil hydrochloride [USAN]
Synonyms
- Alfenta
- Alfentanil
- Alfentanil HCl
- Alfentanil hydrochloride
- EINECS 273-846-3
- R 39209
- Rapifen
- UNII-333JTI7A2M
Systematic Names
- N-(1-(2-(4-Ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl)-4-(methoxymethyl)piperidin-4-yl)-N-phenylpropionamide hydrochloride
- Propanamide, N-(1-(2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl)-4-(methoxymethyl)-4-piperidinyl)-N-phenyl-, monohydrochloride
Registry Numbers
CAS Registry Number
- 69049-06-5
FDA UNII
- 333JTI7A2M
Other Registry Number
- 71124-01-1
System Generated Number
- 0069049065
Molecular Formulas
Molecular Formula
- C21-H32-N6-O3.Cl-H
Molecular Formula Fragments
- C21-H32-N6-O3
- Cl-H
- COMPONENT
Structure Descriptors
InChI
InChI=1S/C21H32N6O3.ClH/c1-4-19(28)27(18-9-7-6-8-10-18)21(17-30-3)11-13-24(14-12-21)15-16-26-20(29)25(5-2)22-23-26;/h6-10H,4-5,11-17H2,1-3H3;1HInChIKey
AQORHZJDCHLLJN-UHFFFAOYSA-NSmiles
Cl.CCN1N=NN(CCN2CCC(COC)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | intravenous | 20mg/kg (20mg/kg) | AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) | Drug Development Research. Vol. 1, Pg. 83, 1981. |
rat | LD50 | intravenous | 47500ug/kg (47.5mg/kg) | BEHAVIORAL: ANALGESIA | Drug Development Research. Vol. 1, Pg. 83, 1981. |