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Substance Name: Pyroglutamyl-histidyl-glycine
RN: 69275-10-1
InChIKey: VTKWFWXOVZIATL-NPPUSCPJSA-N

Note

  • Anorexigenic peptide isolated from urine of patients with anorexia nervosa & from urine of fasted rats & mice.

Classification Codes

  • Anti-Obesity Agents
  • Antineoplastic Agents
  • Appetite Depressants
  • Central Nervous System Agents

Molecular Formula

  • C13-H17-N5-O5

Molecular Weight

  • 323.307
 
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Names and Synonyms

Name of Substance

  • Pyroglutamyl-histidyl-glycine

Synonyms

  • Anorexigenic peptide
  • Colon mitosis inhibitor
  • Pglu-his-gly
  • Pglu-his-gly-OH
  • Pyr-his-gly
  • Pyro-glu-his-gly-OH
  • Ro 14-61332

Systematic Name

  • Glycine, N-(N-(5-oxo-L-prolyl)-L-histidyl)-

Registry Numbers

CAS Registry Number

  • 69275-10-1

Other Registry Number

  • 1163717-06-3

System Generated Number

  • 0069275101

Structure Descriptors

InChI

1S/C13H17N5O5/c19-10-2-1-8(17-10)13(23)18-9(3-7-4-14-6-16-7)12(22)15-5-11(20)21/h4,6-9H,1-3,5H2,(H,15,22)(H,17,19)(H,18,23)(H,20,21)/t7?,8-,9-/m0/s1

InChIKey

VTKWFWXOVZIATL-NPPUSCPJSA-N

Smiles

C(CNC([C@@H](NC([C@H]1NC(CC1)=O)=O)C[C@@H]1C=NC=N1)=O)(=O)O