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Substance Name: Rifamycin [USAN:INN:BAN:DCF]
RN: 6998-60-3
UNII: DU69T8ZZPA
InChIKey: HJYYPODYNSCCOU-ODRIEIDWSA-N
Classification Codes
- Antirheumatic Agents
- Mutation Data
- Reproductive Effect
- Treatment of Traveler's Diarrhea
Molecular Formula
- C37-H47-N-O12
Molecular Weight
- 697.7733
- All
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
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Names and Synonyms
Name of Substance
- Rifamycin SV
- Rifamycin [USAN:INN:BAN:DCF]
Synonyms
- CB-01-11
- EINECS 230-273-3
- M-14
- Rifamicina
- Rifamicina [INN-Spanish]
- Rifamicine SV
- Rifamycin
- Rifamycin SV
- Rifamycine
- Rifamycine [INN-French]
- Rifamycinum
- Rifamycinum [INN-Latin]
- Rifocin
- Rifocyn
- Rifomycin SV
- UNII-DU69T8ZZPA
Systematic Names
- 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate
- Rifamycin
- Rifamycin SV, an antibiotic produced by certain strains of Streptomyces mediterranei, or the same substance produced by any other means
Registry Numbers
CAS Registry Number
- 6998-60-3
FDA UNII
- DU69T8ZZPA
Related Registry Numbers
- 14897-39-3 (unspecified hydrochloride salt)
- 15105-92-7 (mono-hydrochloride salt)
System Generated Number
- 0006998603
Structure Descriptors
InChI
InChI=1S/C37H47NO12/c1-16-11-10-12-17(2)36(46)38-23-15-24(40)26-27(32(23)44)31(43)21(6)34-28(26)35(45)37(8,50-34)48-14-13-25(47-9)18(3)33(49-22(7)39)20(5)30(42)19(4)29(16)41/h10-16,18-20,25,29-30,33,40-44H,1-9H3,(H,38,46)/b11-10+,14-13+,17-12-/t16-,18+,19+,20+,25-,29-,30+,33+,37-/m0/s1InChIKey
HJYYPODYNSCCOU-ODRIEIDWSA-NSmiles
CO[C@H]1\C=C\O[C@@]2(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intracrebral | 5800ug/kg (5.8mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Antibiotics, Series B. Vol. 16, Pg. 312, 1963. |
mouse | LD50 | intraperitoneal | 625mg/kg (625mg/kg) | Experientia. Vol. 16, Pg. 412, 1960. | |
mouse | LD50 | intravenous | 450mg/kg (450mg/kg) | Antimicrobial Agents and Chemotherapy Vol. -, Pg. 359, 1966. | |
mouse | LD50 | oral | 2120mg/kg (2120mg/kg) | Japanese Journal of Antibiotics. Vol. 23, Pg. 242, 1970. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 300 | deg C | EXP | |
log P (octanol-water) | 5.040 | (none) | EST | |
Atmospheric OH Rate Constant | 3.94E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.