Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Cinnarizine dihydrochloride
RN: 7002-58-6
InChIKey: LFZJFDJDYASRCA-JFXLULTRSA-N

Note

  • A piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DISORDERS.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C26-H28-N2.2Cl-H

Molecular Weight

  • 441.443
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • Cinnarizine dihydrochloride

Synonyms

  • 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine dihydrochloride
  • Cinnarizine dihydrochloride
  • Cinnarizine HCl
  • Piperazine, 1-cinnamyl-4-(diphenylmethyl)-, dihydrochloride

Systematic Name

  • Piperazine, 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-, dihydrochloride

Registry Numbers

CAS Registry Number

  • 7002-58-6

Related Registry Number

  • 298-57-7 (Parent)

System Generated Number

  • 0007002586

Molecular Formulas

Molecular Formula

  • C26-H28-N2.2Cl-H

Molecular Formula Fragments

  • C26-H28-N2
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C26H28N2.2ClH/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25;;/h1-17,26H,18-22H2;2*1H/b13-10+;;

InChIKey

LFZJFDJDYASRCA-JFXLULTRSA-N

Smiles

N1(CCN(CC1)C\C=C\c1ccccc1)C(c1ccccc1)c1ccccc1.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 47600ug/kg (47.6mg/kg)   United States Patent Document. Vol. #4883797,