Important Announcement

X

ChemIDplus is moving to PubChem in December 2022.
Please see the NLM Technical Bulletin article for more information.

Skip Navigation
ChemIDplus LiteBrowseAdvanced

Substance Name: Rilpivirine hydrochloride [USAN]
RN: 700361-47-3
UNII: 212WAX8KDD
InChIKey: KZVVGZKAVZUACK-BJILWQEISA-N

Classification Codes

  • Anti-Infective Agents
  • Anti-Retroviral Agents
  • Antiviral Agents
  • Enzyme Inhibitors
  • Nucleic Acid Synthesis Inhibitors
  • Reverse Transcriptase Inhibitors
  • Treatment of HIV Infection

Molecular Formula

  • C22-H18-N6.Cl-H

Molecular Weight

  • 402.8871
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Rilpivirine hydrochloride
  • Rilpivirine hydrochloride [USAN]

Synonyms

  • 4-((4-((4-((1E)-2-Cyanoethenyl)-2,6-dimethylphenyl)amino)pyrimidin-2- yl)amino)benzonitrile
  • Benzonitrile, 4-((4-((4-((1e)-2-cyanoethenyl)-2,6-dimethylphenyl)amino)-2-pyrimidinyl)amino)-, hydrochloride (1:1)
  • Endurant
  • Rilpivirine hydrochloride
  • TMC278 hydrochloride
  • UNII-212WAX8KDD

Systematic Name

  • Benzonitrile, 4-((4-((4-((1E)-2-cyanoethenyl)-2,6-dimethylphenyl)amino)-2- pyrimidinyl)amino)-, hydrochloride (1:1)

Registry Numbers

CAS Registry Number

  • 700361-47-3

FDA UNII

  • 212WAX8KDD

System Generated Number

  • 0700361473

Molecular Formulas

Molecular Formula

  • C22-H18-N6.Cl-H

Molecular Formula Fragments

  • C22-H18-N6
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C22H18N6.ClH/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19;/h3-9,11-13H,1-2H3,(H2,25,26,27,28);1H/b4-3+;

InChIKey

KZVVGZKAVZUACK-BJILWQEISA-N

Smiles

Cl.Cc1cc(\C=C\C#N)cc(C)c1Nc2ccnc(Nc3ccc(cc3)C#N)n2