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Substance Name: Amisulpride [INN:BAN]
RN: 71675-85-9
UNII: 8110R61I4U


  • A benzamide derivative that is used as an antipsychotic agent for the treatment of schizophrenia. It is also used as an antidepressive agent.

Molecular Formula

  • C17-H27-N3-O4-S

Molecular Weight

  • 369.483

Classification Codes

  • Antidepressive Agents
  • Antidepressive Agents, Second-Generation
  • Antipsychotic Agents
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Dopamine Agents
  • Dopamine Antagonists
  • Drug / Therapeutic Agent
  • Neurotransmitter Agents
  • Psychotropic Drugs
  • Tranquilizing Agents
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Names and Synonyms

Name of Substance

  • Amisulpride [INN:BAN]
  • Sultopride

MeSH Heading

  • Amisulpride


  • 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-anisamid
  • 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide
  • 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide
  • Aminosultopride
  • Amisulprida
  • Amisulprida [INN-Spanish]
  • Amisulpride
  • Amisulpridum
  • Amisulpridum [INN-Latin]
  • APD421
  • DAN 2163
  • EINECS 275-831-7
  • NSC 760085
  • Solian
  • Sulpitac
  • UNII-8110R61I4U

Systematic Names

  • 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide
  • Amisulpride
  • Benzamide, 4-amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxy-

Registry Numbers

CAS Registry Number

  • 71675-85-9


  • 8110R61I4U

System Generated Number

  • 0071675859

Structure Descriptors








Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 175mg/kg (175mg/kg)   United States Patent Document. Vol. #4401822,
mouse LD50 intravenous 56mg/kg (56mg/kg)   United States Patent Document. Vol. #4401822,
mouse LD50 oral 1024mg/kg (1024mg/kg)   United States Patent Document. Vol. #4401822,
mouse LD50 subcutaneous 224mg/kg (224mg/kg)   United States Patent Document. Vol. #4401822,

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 126-127 deg C   EXP
pKa Dissociation Constant 9.37 (none)   EXP
log P (octanol-water) 1.1 (none)   EXP
Water Solubility 543 mg/L 25 EST
Vapor Pressure 2.63E-12 mm Hg 25 EST
Henry's Law Constant 2.12E-20 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 3.19E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.