Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Borrelidin
RN: 7184-60-3
InChIKey: OJCKRNPLOZHAOU-UGKRXNSESA-N

Note

  • Isolated from Streptomyces albovinaceous; active against Treponema hyodysenteriae.

Classification Codes

  • Drug / Therapeutic Agent
  • Natural Product

Molecular Formula

  • C28-H43-N-O6

Molecular Weight

  • 489.649
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Borrelidin
  • Treponemycin

Synonyms

  • 5-18-09-00385 (Beilstein Handbook Reference)
  • BRN 0066270
  • NSC 216128

Systematic Names

  • 2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)-cyclopentanecar boxylic acid
  • Borrelidin
  • Treponemycin

Registry Numbers

CAS Registry Number

  • 7184-60-3

Other Registry Number

  • 97328-74-0

System Generated Number

  • 0007184603

Structure Descriptors

InChI

1S/C28H43NO6/c1-17-12-18(2)14-20(4)27(32)21(16-29)8-5-6-11-25(22-9-7-10-23(22)28(33)34)35-26(31)15-24(30)19(3)13-17/h5-6,8,17-20,22-25,27,30,32H,7,9-15H2,1-4H3,(H,33,34)/b6-5+,21-8-/t17-,18+,19-,20-,22+,23+,24-,25-,27+/m0/s1

InChIKey

OJCKRNPLOZHAOU-UGKRXNSESA-N

Smiles

C1C[C@H]([C@@H](C1)[C@@H]1CC=CC=C([C@@H]([C@H](C[C@H](C)C[C@H](C)C[C@@H]([C@H](CC(=O)O1)O)C)C)O)C#N)C(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 intramuscular 74mg/kg (74mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 2, Pg. 1198, 1978.
mouse LD50 intravenous 39mg/kg (39mg/kg)   Journal of Clinical Investigation. Vol. 28, Pg. 1047, 1949.
mouse LD50 subcutaneous 75mg/kg (75mg/kg)   Journal of Clinical Investigation. Vol. 28, Pg. 1047, 1949.
rat LD50 intravenous 2mg/kg (2mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 2, Pg. 1198, 1978.
rat LD50 subcutaneous 1780ug/kg (1.78mg/kg)   Journal of Clinical Investigation. Vol. 28, Pg. 1047, 1949.