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Substance Name: Methoxychlor [BSI:ISO]
RN: 72-43-5
UNII: RIA79UD69L
InChIKey: IAKOZHOLGAGEJT-UHFFFAOYSA-N

Note

  • An insecticide. Methoxychlor has estrogenic effects in mammals, among other effects.

Molecular Formula

  • C16-H15-Cl3-O2

Molecular Weight

  • 345.651
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Human Data
  • Insecticide
  • Insecticides
  • Mutation Data
  • Pesticides
  • Reproductive Effect
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 61
  • 2011 CERCLA Priority List, Rank: 55
  • Overall Carcinogenic Evaluation: Group 3
  • Reportable Quantity (RQ) = 1 lb
  • TWA 10 mg/m3; Not classifiable as a human carcinogen
  • TWA 15 mg/m3 total dust

Names and Synonyms

Results Name

  • Methoxychlor [BSI:ISO]

Name of Substance

  • Methoxychlor
  • Methoxychlor [BSI:ISO]

MeSH Heading

  • Methoxychlor

Synonyms

  • 1,1'-(2,2,2-Trichloroethylidene)bis(4-methoxybenzene)
  • 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan
  • 1,1,1-Trichlor-2,2-bis(4-methoxy-phenyl)-aethan [German]
  • 1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane
  • 1,1,1-Trichloro-2,2-bis(p-anisyl)ethane
  • 1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane
  • 1,1,1-Trichloro-2,2-di(4-methoxyphenyl)ethane
  • 1,1-Bis(p-methoxyphenyl)-2,2,2-trichloroethane
  • 2,2,2-Trichloro-1,1-bis(4-methoxyphenyl)ethane
  • 2,2-Bis(p-anisyl)-1,1,1-trichloroethane
  • 2,2-Bis(p-methoxyphenyl)-1,1,1-trichloroethane
  • 2,2-Di-(p-methoxyphenyl)-1,1,1-trichloroethane
  • 2,2-Di-p-anisyl-1,1,1-trichloroethane
  • 4,4-(2,2,2-Trichloroethylidene)dianisole
  • 4-06-00-06691 (Beilstein Handbook Reference)
  • BRN 2057367
  • Caswell No. 550
  • CCRIS 380
  • Chemform
  • Dianisyl trichloroethane
  • Dianisyltrichlorethane
  • Dimethoxy-DDT
  • DMDT
  • EINECS 200-779-9
  • ENT 1,716
  • EPA Pesticide Chemical Code 034001
  • Ethane, 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-
  • Ethane, 2,2-bis(p-anisyl)-1,1,1-trichloro-
  • Higalmetox
  • HSDB 1173
  • Maralate
  • Marlate
  • Methoxcide
  • Methoxy-DDT
  • Methoxychlor
  • Methoxychlor 2 EC
  • Methoxychlor, technical
  • Methoxychlore
  • Methoxychlore [ISO-French]
  • Metoksychlor
  • Metoksychlor [Polish]
  • Metox
  • Mezox K
  • Moxie
  • MXC
  • NCI-C00497
  • NSC 8945
  • OMS 466
  • p,p'-Dimethoxydiphenyltrichloroethane
  • p,p'-Dwumetoksydwufenylotrojchloroetan
  • p,p'-Dwumetoksydwufenylotrojchloroetan [Polish]
  • p,p'-Methoxychlor
  • RCRA waste number U247
  • UNII-RIA79UD69L

Systematic Names

  • Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-methoxy-
  • Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-methoxy- (9CI)
  • Ethane, 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-
  • Methoxychlor

Superlist Names

  • Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-methoxy-
  • Methoxychlor
  • RCRA waste no. U247

Registry Numbers

CAS Registry Number

  • 72-43-5

FDA UNII

  • RIA79UD69L

System Generated Number

  • 0000072435

Structure Descriptors

InChI

1S/C16H15Cl3O2/c1-20-13-7-3-11(4-8-13)15(16(17,18)19)12-5-9-14(21-2)10-6-12/h3-10,15H,1-2H3

InChIKey

IAKOZHOLGAGEJT-UHFFFAOYSA-N

Smiles

C(c1ccc(OC)cc1)(c1ccc(OC)cc1)C(Cl)(Cl)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
duck LD50 oral > 2gm/kg (2000mg/kg)   Pesticide Manual. Vol. 9, Pg. 574, 1991.
hamster LD50 intraperitoneal 500mg/kg (500mg/kg)   Archives of Toxicology. Vol. 58, Pg. 152, 1986.
human LDLo oral 6430mg/kg (6430mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 705, 1966.
human TDLo skin 2414mg/kg (2414mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 705, 1966.
mouse LD50 oral 510mg/kg (510mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

BEHAVIORAL: EXCITEMENT
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 58(1), Pg. 44, 1993.
rabbit LD50 oral > 6gm/kg (6000mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 16, 1978.
rabbit LD50 skin > 6gm/kg (6000mg/kg)   World Review of Pest Control. Vol. 3, Pg. 28, 1964.
rat LD50 oral 1855mg/kg (1855mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: ATAXIA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 58(1), Pg. 44, 1993.
rat LD50 skin > 6gm/kg (6000mg/kg)   "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956Vol. -, Pg. 1, 1956.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 87 deg C   EXP
Boiling Point 346 deg C   EXP
log P (octanol-water) 5.08 (none)   EXP
Water Solubility 0.1 mg/L 25 EXP
Vapor Pressure 2.58E-06 mm Hg 25 EST
Henry's Law Constant 2.03E-07 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 5.35E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.