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Substance Name: Trypan Blue
RN: 72-57-1
UNII: I2ZWO3LS3M
InChIKey: GLNADSQYFUSGOU-GPTZEZBUSA-J
Note
- A diazo-naphthalene sulfonate that is widely used as a stain.
Molecular Formula
- C34-H28-N6-O14-S4.4Na
Molecular Weight
- 960.8156
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Coloring Agents
- Drug / Therapeutic Agent
- Mutation Data
- Reproductive Effect
- Tumor Data
Superlist Classification Codes
- Overall Carcinogenic Evaluation: Group 2B
- Reportable Quantity (RQ) = 10 lb
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Names and Synonyms
Name of Substance
- Trypan Blue
MeSH Heading
- Trypan Blue
Synonyms
- AI3-26698
- Amanil Sky Blue R
- Azidinblau 3B
- Azidine Blue 3B
- Azurro diretto 3B
- Bencidal Blue 3B
- Benzaminblau 3B
- Benzamine Blue
- Benzamine Blue 3B
- Benzanil Blue 3BN
- Benzanil Blue R
- Benzo Blue
- Benzo Blue 3B
- Benzo Blue 3BS
- Benzoblau 3B
- Bleu diamine
- Bleu diazole N 3B
- Bleu directe 3B
- Bleu trypane N
- Bleue diretto 3B
- Blue 3B
- Blue EMB
- Brasilamina Blue 3B
- Brasilazina Blue 3B
- C.I. 23850
- C.I. Direct Blue 14
- C.I. Direct Blue 14, tetrasodium salt
- CCRIS 616
- Centraline Blue 3B
- Chloramiblau 3B
- Chloramine Blue
- Chloramine Blue 3B
- Chlorazol Blue 3B
- Chrome Leather Blue 3B
- Congo Blue
- Congoblau 3B
- Cresotine Blue 3B
- Diaminblau 3B
- Diamine Blue 3B
- Diamineblue
- Diaminine Blue
- Dianil Blue
- Dianil Blue H3G
- Dianilblau
- Dianilblau H3G
- Diaphtamine Blue TH
- Diazine Blue 3B
- Diazol Blue 3B
- Diphenyl Blue 3B
- Direct Blue 14
- Direct Blue 3B
- Direct Blue 3BX
- Direct Blue D3B
- Direct Blue H3G
- Direct Blue M3B
- Directakol Blue 3BL
- Directblau 3B
- EINECS 200-786-7
- Hispamin Blue 3BX
- HSDB 2945
- Membraneblue
- Modr Prima 14
- Modr Prima 14 [Czech]
- Modr Trypanova
- Modr Trypanova [Czech]
- Naphthaminblau 3BX
- Naphthamine Blue 3BX
- Naphthylamine Blue
- NCI C61289
- Niagara Blue
- Niagara Blue 3B
- NSC 11247
- Orion Blue 3B
- Paramine Blue 3B
- Parkibleu
- Parkipan
- Pontamine Blue 3BX
- Pyrazol Blue 3B
- Pyrotropblau
- RCRA waste number U236
- Renolblau 3B
- Sodium ditolyl-diazobis-8-amino-1-naphthol-3,6-disulfonate
- Sodium ditolyldisazobis-8-amino-1-naphthol-3,6-disulfonate
- Sodium ditolyldisazobis-8-amino-1-naphthol-3,6-disulphonate
- Trianol Direct Blue 3B
- Triazolblau 3BX
- Tripan Blue
- Trypan (Congo) Blue
- Trypan Blue
- Trypan Blue BPC
- Trypanblau
- Trypanblau [German]
- Trypane Blue
- UNII-I2ZWO3LS3M
- Vision Blue
- VisionBlue
Systematic Names
- 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2,1-diazenediyl))bis(5-amino-4-hydroxy-, sodium salt (1:4)
- 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(azo))bis(5-amino-4-hydroxy-, tetrasodium salt
- C.I. Direct Blue 14
- C.I. Direct Blue 14, tetrasodium salt (8CI)
- Tetrasodium 3,3'-((3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(azo))bis(5-amino-4-hydroxynaphthalene-2,7-disulphonate)
Superlist Names
- 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(azo))bis(5-amino-4-hydroxy-, tetrasodium salt
- RCRA waste no. U236
- Trypan Blue
- Trypan blue (commercial grade)
Registry Numbers
CAS Registry Number
- 72-57-1
FDA UNII
- I2ZWO3LS3M
Other Registry Number
- 179472-55-0
System Generated Number
- 0000072571
Molecular Formulas
Molecular Formula
- C34-H28-N6-O14-S4.4Na
Molecular Formula Fragments
- C34-H28-N6-O14-S4
- COMPONENT
- Na
Structure Descriptors
InChI
1S/C34H28N6O14S4.4Na/c1-15-7-17(3-5-25(15)37-39-31-27(57(49,50)51)11-19-9-21(55(43,44)45)13-23(35)29(19)33(31)41)18-4-6-26(16(2)8-18)38-40-32-28(58(52,53)54)12-20-10-22(56(46,47)48)14-24(36)30(20)34(32)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-37+,40-38+;;;;InChIKey
GLNADSQYFUSGOU-GPTZEZBUSA-JSmiles
c12c(cc(c(c1O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LDLo | intraperitoneal | 250mg/kg (250mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934. |
guinea pig | LDLo | subcutaneous | 300mg/kg (300mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934. |
mouse | LD50 | intravenous | 328mg/kg (328mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972. | |
mouse | LD50 | subcutaneous | 267mg/kg (267mg/kg) | Naunyn-Schmiedebergs Archiv fuer Pharmakologie. Vol. 267, Pg. 31, 1970. | |
mouse | LDLo | intraperitoneal | 350mg/kg (350mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934. |
rabbit | LDLo | intraperitoneal | 400mg/kg (400mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934. |
rabbit | LDLo | intravenous | 100mg/kg (100mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934. |
rat | LD50 | oral | 6200mg/kg (6200mg/kg) | Office of Toxic Substances Report. Vol. OTS, | |
rat | LDLo | intraperitoneal | 300mg/kg (300mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934. |
rat | LDLo | intravenous | 300mg/kg (300mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934. |
rat | LDLo | subcutaneous | 300mg/kg (300mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Proceedings of the Society for Experimental Biology and Medicine. Vol. 31, Pg. 825, 1934. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | >300 | deg C | EXP | |
log P (octanol-water) | -0.120 | (none) | EST | |
Atmospheric OH Rate Constant | 2.27E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.