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Substance Name: Losulazine [INN]
RN: 72141-57-2
UNII: O2978JQ9B7
InChIKey: SYJKIRZBDWNJSB-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C27-H22-F4-N4-O3-S

Molecular Weight

  • 558.554
 
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Names and Synonyms

Name of Substance

  • Losulazine [INN]

Synonyms

  • 1-((4-Fluorophenyl)sulfonyl)-4-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl)piperazine
  • BRN 6257178
  • Losulazina
  • Losulazina [Spanish]
  • Losulazine
  • Losulazinum
  • Losulazinum [Latin]
  • UNII-O2978JQ9B7

Systematic Name

  • Piperazine, 1-((4-fluorophenyl)sulfonyl)-4-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl)-

Registry Numbers

CAS Registry Number

  • 72141-57-2

FDA UNII

  • O2978JQ9B7

System Generated Number

  • 0072141572

Structure Descriptors

InChI

1S/C27H22F4N4O3S/c28-20-4-8-22(9-5-20)39(37,38)35-15-13-34(14-16-35)26(36)18-1-6-21(7-2-18)33-24-11-12-32-25-17-19(27(29,30)31)3-10-23(24)25/h1-12,17H,13-16H2,(H,32,33)

InChIKey

SYJKIRZBDWNJSB-UHFFFAOYSA-N

Smiles

N1(CCN(CC1)C(c1ccc(cc1)Nc1ccnc2cc(ccc12)C(F)(F)F)=O)S(=O)(=O)c1ccc(cc1)F

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral > 3160mg/kg (3160mg/kg)   Journal of Medicinal Chemistry. Vol. 29, Pg. 133, 1986.