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Substance Name: Prolyl oligopeptidase
RN: 72162-84-6


  • Cleaves dipeptides from N-terminal end of peptide chain if penultimate residue is proline; before 1992 prolyl endopeptidase (thiol-dependent) was EC; GenBank AF010298 (Sphingomonase capsulata); PREPL A human is a member of the prolyl oligopeptidase family, lacking catalytic activity; RefSeq NM_006036 (human).
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Names and Synonyms

Name of Substance

  • Prolyl oligopeptidase


  • Post-proline cleaving enzyme
  • Post-proline endopeptidase
  • PREPL A protein, human
  • PREPL protein, human
  • Proline endopeptidase
  • Proline specific endopeptidase
  • Prolyl endopeptidase
  • Prolyl endopeptidase (thiol-dependent)
  • Prolyl endopeptidase I
  • Prolyl endopeptidase-like protein, human
  • Prolyl oligopeptidase Tc80
  • Tc80 prolyl oligopeptidase, Trypanosoma cruzi

Registry Numbers

CAS Registry Number

  • 72162-84-6

System Generated Number

  • 0072162846