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Substance Name: hlyA protein, Listeria monocytogenes
RN: 72270-41-8


  • From Listeria monocytogenes; sulfhydryl-activated toxin; is able to lyse cholesterol containing membranes; can be reversibly inactivated by oxidation; cholesterol is the receptor for the binding of these toxins to eukaryotic cell membranes.

Molecular Formula

  • Unspecified

Classification Code

  • Natural Product
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Names and Synonyms

Name of Substance

  • hlyA protein, Listeria monocytogenes


  • Ivanolysin O
  • Listeriolysins (Listeria monocytogenes)

Systematic Name

  • Listeriolysin

Registry Numbers

CAS Registry Number

  • 72270-41-8

System Generated Number

  • 0072270418


Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo intravenous 24ug/kg (0.024mg/kg)   "Bcterial Toxins and Cell Membranes", Jeljaszewicz, J., and T. Wadstroem, eds., London, UK, Academic Press Ltd., 1978Vol. -, Pg. 140, 1978.