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Substance Name: Propetamide [INN]
RN: 730-07-4
UNII: U9R24EH050
InChIKey: VVUMWAHNKOLVSN-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C14-H22-N2-O2

Molecular Weight

  • 250.34
 
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Names and Synonyms

Name of Substance

  • Propetamide
  • Propetamide [INN]

Synonyms

  • 2-((4-Ethoxyphenyl)amino)-N-propylpropanamide
  • 2-p-Phenetidino-N-propylpropionamide
  • BRN 2856558
  • FC 379
  • p-Phenetidine-alpha-N-n-propylpropionamide
  • Propetamida
  • Propetamida [INN-Spanish]
  • Propetamide
  • Propetamidum
  • Propetamidum [INN-Latin]
  • UNII-U9R24EH050

Systematic Names

  • 2-p-Phenetidino-N-propylpropionamide
  • d,1-alpha(p-Ethoxyphenylamino)-N-n-propylpropionamide
  • Propanamide, 2-((4-ethoxyphenyl)amino)-N-propyl-
  • Propionamide, 2-p-phenetidino-N-propyl- (8CI)

Registry Numbers

CAS Registry Number

  • 730-07-4

FDA UNII

  • U9R24EH050

System Generated Number

  • 0000730074

Structure Descriptors

InChI

1S/C14H22N2O2/c1-4-10-15-14(17)11(3)16-12-6-8-13(9-7-12)18-5-2/h6-9,11,16H,4-5,10H2,1-3H3,(H,15,17)

InChIKey

VVUMWAHNKOLVSN-UHFFFAOYSA-N

Smiles

c1cc(ccc1OCC)N[C@@H](C(=O)NCCC)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1330mg/kg (1330mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 164, Pg. 331, 1966.
mouse LD50 oral 2100mg/kg (2100mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 164, Pg. 331, 1966.
rat LD50 intraperitoneal 1350mg/kg (1350mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 164, Pg. 331, 1966.
rat LD50 oral 3gm/kg (3000mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 164, Pg. 331, 1966.