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Substance Name: Florfenicol [USAN:INN:BAN]
RN: 73231-34-2
UNII: 9J97307Y1H
InChIKey: AYIRNRDRBQJXIF-NXEZZACHSA-N

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antibacterial (Veterinary)
  • Drug / Therapeutic Agent

Molecular Formula

  • C12-H14-Cl2-F-N-O4-S

Molecular Weight

  • 358.2156
 
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Names and Synonyms

Name of Substance

  • Florfenicol
  • Florfenicol [USAN:INN:BAN]

Synonyms

  • (-)-Florfenicol
  • 2,2-Dichloro-N-((alphaS,betaR)-alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide
  • 2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
  • Acetamide, 2,2-dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-, (R-(R*,S*))-
  • D-threo-2,2-Dichloro-N-(alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide
  • Florfenicol
  • Nuflor
  • Nuflor gold
  • Sch 25298
  • Sch-25298
  • UNII-9J97307Y1H

Systematic Names

  • Acetamide, 2,2-dichloro-N-((1S,2R)-1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-
  • Acetamide, 2,2-dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)-, (R-(R*,S*))-
  • Benzenesulfonic acid, 4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-, methyl ester, (R-(R*,S*))-

Mixture Name

  • Resflor gold

Registry Numbers

CAS Registry Number

  • 73231-34-2

FDA UNII

  • 9J97307Y1H

Other Registry Numbers

  • 76639-94-6
  • 81588-76-3

System Generated Number

  • 0073231342

Structure Descriptors

InChI

1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1

InChIKey

AYIRNRDRBQJXIF-NXEZZACHSA-N

Smiles

CS(=O)(=O)c1ccc(cc1)[C@H]([C@@H](CF)NC(=O)C(Cl)Cl)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 100mg/kg (100mg/kg)   Drugs of the Future. Vol. 7, Pg. 172, 1982.