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Substance Name: Dihydralazine sulfate
RN: 7327-87-9
UNII: 1C2B1W91NK
InChIKey: BWHAMWGGORIDBK-UHFFFAOYSA-N

Note

  • An antihypertensive agent with actions and uses similar to those of HYDRALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p354)

Molecular Formula

  • C8-H10-N6.H2-O4-S

Molecular Weight

  • 288.2868
 

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
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Names and Synonyms

Name of Substance

  • Dihydralazine sulfate

Synonyms

  • 1,4-Dihydrazinophthalazine sulfate
  • CCRIS 5386
  • Depressan
  • Dihydralazine sulfate
  • EINECS 230-808-0
  • Nepresol
  • Sulfate de dihydralazine
  • Sulfate de dihydralazine [French]
  • UNII-1C2B1W91NK

Systematic Names

  • 1,4-Dihydrazinophthalazine hydrogen sulfate
  • Dihydralazine sulfate
  • Dihydralazine sulphate
  • Phthalazine, 1,4-dihydrazino-, sulfate (1:1)

Registry Numbers

CAS Registry Number

  • 7327-87-9

FDA UNII

  • 1C2B1W91NK

System Generated Number

  • 0007327879

Molecular Formulas

Molecular Formula

  • C8-H10-N6.H2-O4-S

Molecular Formula Fragments

  • C8-H10-N6
  • COMPONENT
  • H2-O4-S

Structure Descriptors

InChI

InChI=1S/C8H10N6.H2O4S/c9-11-7-5-3-1-2-4-6(5)8(12-10)14-13-7;1-5(2,3)4/h1-4H,9-10H2,(H,11,13)(H,12,14);(H2,1,2,3,4)

InChIKey

BWHAMWGGORIDBK-UHFFFAOYSA-N

Smiles

NNC1=NN\C(=N/N)\c2ccccc12.OS(=O)(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 159mg/kg (159mg/kg)   Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 283, 1970.
mouse LD50 oral 400mg/kg (400mg/kg)   Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 284, 1970.
mouse LD50 subcutaneous 223mg/kg (223mg/kg)   Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 283, 1970.
rat LD50 oral 400mg/kg (400mg/kg)   French Demande Patent Document. Vol. #2321890,